全球结核杆菌耐药问题日趋严重,儿童耐药结核的发生率也在增加,儿童耐药结核主要来自排结核菌的成人,不正规的抗结核治疗,使儿童易感染原发耐药结核菌,很少是因治疗后的获得性耐药。儿童耐药结核的诊断十分困难,对于未能分离出耐药结核菌的患儿,依据分析感染来源的结核患者对抗结核药物的耐药情况和耐药类型及抗结核治疗的效果作出诊断。儿童耐药结核治疗原则与成人相同,要求长疗程、多种抗结核药物的联合治疗。 The global drug resistance problem of Mycobacterium tuberculosis is worsening day by day, and the incidence of drug-resistant tuberculosis in children is also increasing. Drug-resistant tuberculosis in children mainly comes from adults with Mycobacterium tuberculosis, and the irregular anti-tuberculosis treatment makes children susceptible to primary drug- Few are acquired resistance after treatment. The diagnosis of drug-resistant TB in children is very difficult. For children who can not isolate drug-resistant TB, diagnosis is made based on the analysis of drug resistance and type of drug-resistant tuberculosis in TB patients infected with TB and the effect of anti-TB treatment. Children with drug-resistant tuberculosis treatment principles and adults the same, requiring a long course of treatment, a variety of anti-TB drugs combined treatment.