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为证实高原低氧环境对胎儿宫内生长发育的影响,我们调查了拉萨市(海拔3,658m,大气压490mnmHg)15例藏族和16例汉族新生儿的出生体重、身长、头围,并测定了脐带血的血红蛋白浓度和血球压积。结果显示:藏族新生儿的出生体重、身长和头围测定值分别比汉族新生儿高311g、2.4cm和1.9cm(P值均小于0.05);脐带血血球压积和血红蛋白浓度分别低6.3%(P<0.001)和1.8g/dl(P<0.01)。提示:高原低氧环境影响胎儿宫内生长发育。世居高原居民由于具有对高原低氧环境的遗传性适应能力,因此代偿了缺氧对胎儿宫内生长发育的影响。
In order to confirm the impact of plateau hypoxia on intrauterine growth and development, we investigated the birth weight, body length and head circumference of 15 Tibetan and 16 Han newborns in Lhasa (elevation 3,658 m, atmospheric pressure 490 mnmHg) Cord blood hemoglobin concentration and hematocrit. The results showed that the birth weight, body length and head circumference of Tibetan newborns were 311g, 2.4cm and 1.9cm higher than those of Han newborns respectively (P <0.05). The cord blood hemoglobin and hemoglobin concentrations were respectively Low 6.3% (P <0.001) and 1.8 g / dl (P <0.01). Hint: High altitude hypoxic environment affects fetal growth and development. Inhabitants of plateau have compensated for the effect of hypoxia on intrauterine growth due to their hereditary adaptability to plateau hypoxia.