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[目的]研究代谢综合征对急性胰腺炎病情发展的影响及预后。[方法]回顾分析290例急性胰腺炎患者的临床资料,根据其是否伴有代谢综合征(MS),分为MS组(140例)及非MS组(150例),将2组患者临床疗效、C反应蛋白、血钙、血氧分压、住院时间、重症胰腺炎的发生率、Ranson评分、APACHE II评分、局部及全身并发症以及死亡的发生率进行比较。[结果]MS组较非MS组临床疗效差,C反应蛋白高,血钙,血氧分压低,住院时间长(均P<0.05),SAP的患病率、Ranson评分、APACHE II评分高(P<0.01),局部及全身并发症高(P<0.01)以及死亡发生率高(P<0.05),差异均有统计学意义。[结论]MS影响着急性胰腺炎的病情、分型及预后,临床对急性胰腺炎患者是否存在MS的评估可作为判断急性胰腺炎病情严重程度、预后的客观、快速的评价指标之一,值得临床推广应用。
[Objective] To study the influence and prognosis of metabolic syndrome on the progression of acute pancreatitis. [Methods] The clinical data of 290 patients with acute pancreatitis were retrospectively analyzed. According to whether they were associated with metabolic syndrome (MS), the clinical data were divided into MS group (140 cases) and non-MS group (150 cases) , C-reactive protein, serum calcium, partial pressure of oxygen, hospital stay, incidence of severe pancreatitis, Ranson score, APACHE II score, local and systemic complications, and the incidence of death. [Results] The clinical efficacy, high C-reactive protein, low serum calcium, partial pressure of oxygen and long hospital stay in MS group were significantly higher than those in non-MS group (P <0.05), SAP prevalence, Ranson score and APACHE II score were higher P <0.01). Local and systemic complications were high (P <0.01) and the incidence of death was higher (P <0.05). The differences were statistically significant. [Conclusion] MS affects the condition, classification and prognosis of acute pancreatitis. The clinical evaluation of the presence of MS in patients with acute pancreatitis can be used as an objective and rapid evaluation index to judge the severity and prognosis of acute pancreatitis. Clinical application.