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目的探讨胃肠间质瘤的临床病理特点及其治疗方法。方法对2003-2008年收治的31例胃肠间质瘤患者的临床资料进行回顾性分析。结果患者主要临床症状为黑便、腹部不适、腹部肿块、贫血和肠梗阻等。31例患者均行手术治疗,标本经病理及免疫组织化学证实。组织学形态以梭形细胞为主,CD117、CD34阳性率分别为100%及58%。高度危险性6例,中度危险性9例,低度危险性7例和极低度危险性9例。结论胃肠间质瘤治疗首选外科手术,对复发者应积极再次手术,可延长生存期。
Objective To investigate the clinicopathological features and treatment of gastrointestinal stromal tumors. Methods The clinical data of 31 patients with gastrointestinal stromal tumors admitted from 2003 to 2008 were retrospectively analyzed. Results The main clinical symptoms of the patient were melena, abdominal discomfort, abdominal mass, anemia and intestinal obstruction. All 31 patients underwent surgical treatment. The specimens were confirmed by pathology and immunohistochemistry. The histological morphology was mainly spindle cells. The positive rates of CD117 and CD34 were 100% and 58%, respectively. There were 6 cases of high risk, 9 cases of moderate risk, 7 cases of low risk and 9 cases of extremely low risk. Conclusions The first choice for surgical treatment of gastrointestinal stromal tumors is surgery. Recurrence should be actively re-operation and prolong survival.