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目的分析成人紫癜性肾炎应用甲泼尼龙冲击治疗的临床效果。方法 50例成人紫癜性肾炎患者,随机分为对照组与观察组,各25例。对照组给予常规治疗,观察组在常规治疗基础上施以甲泼尼龙冲击治疗,比较两组患者临床疗效。结果对照组治疗总有效率为68.00%,低于观察组的92.00%,两组比较差异有统计学意义(χ2=17.5751,P<0.05)。结论甲泼尼龙冲击用于成人紫癜性肾炎治疗,有显著疗效,且安全性较高,具有临床推广价值。
Objective To analyze the clinical effect of methylprednisolone in adult purpuric nephritis. Methods Fifty adult patients with purpuric nephritis were randomly divided into control group and observation group, with 25 cases in each. The control group was given routine treatment. The observation group was treated with methylprednisolone on the basis of routine treatment. The clinical efficacy of the two groups was compared. Results The total effective rate of the control group was 68.00%, which was lower than that of the observation group (92.00%). The difference between the two groups was statistically significant (χ2 = 17.5751, P <0.05). Conclusion Methylprednisolone for the treatment of adult purpura nephritis, a significant effect, and high safety, with clinical value.