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本文选用骨髓片４４６例、血片１７４例，其中急性白血病２１２例，慢性白血病３７例，其它白血病２２例，骨髓增生异常综合征５２例，非白血病８０例，正常人４３例。应用ＰＬＯＴＯＮ及本室改良法，检测核仁组成区相关嗜银蛋白（ＡｇＮＯＲｓ），ＡｇＮＯＲｓ颗粒／核及特殊鼻常嗜银染色区百分率及内外颗粒总合，代替检测１００个有核细胞ＡｇＮＯＲｓ嗜银颗粒面积（ＧＡ），并测定１００个有核细胞核面积（ＮＡ）、ＧＡ和Ｇ／Ａ（嗜银颗粒／有核细胞核面积）的比值三项指标，结果表明急性白血病ＡｇＮＯＲｓ颗粒／核为４．４３±０．９８，特殊异常嗜银染色区占１９．８％；期余ＡｇＮＯＲｓ颗粒／核分别为：慢性白血病为３．０３±０．８２，其它白血病为４．３５±１．４９，骨髓增生异常综合征为４．３１±１．３８，非白血病为２．８５±０．９５；正常人为１．４９±０．３７。
This article selected 446 cases of bone marrow tablets, 174 cases of blood, of which 212 cases of acute leukemia, chronic leukemia in 37 cases, 22 cases of other leukemia, 52 cases of myelodysplastic syndrome, 80 cases of non-leukemia, 43 cases of normal people. Using PLOTON and our laboratory’s modified method to detect AgNORs, AgNORs/nuclear and special nasal algose staining areas and aggregates of internal and external granules, instead of detecting 100 nucleated cells AgNORs argyrophils The area of particles (GA) was measured and the ratio of 100 nucleated nuclear area (NA), GA, and G/A ratio (arbitrary granules/nucleated nuclear area) was determined. The results showed that AgNORs particles/nuclei of acute leukemia were 4. 43±0.98, special abnormal silver stained area accounted for 19.8%; AgNORs particles/nucleus were: chronic leukemia was 3.03±0.82, other leukemia was 4.35±1.49, bone marrow The abnormality rate was 4.31±1.38 in non-leukemia patients, 2.85±0.95 in non-leukemia patients and 1.49±0.37 in normal controls.