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目的探讨心理干预加文拉法星治疗在冠状动脉支架植入术后抑郁障碍患者中的作用。方法将符合诊断标准的冠状动脉支架植入术后患者随机分为研究组(A组)和对照组(B组),并用焦虑自评量表(SAS)、抑郁自评量表(SDS)进行焦虑抑郁水平测定,进行不同时段和2组间比较。结果心理行为干预及药物治疗前A组,SAS、SDS分别为63±7、64±6,B组为63±8,65±7,2组对比差异无统计学意义(P>0.05)。心理行为干预及药物治疗后,A组术后8h、1、3、5周SAS评分分别为63±7、52±5、48±6、44±4;SDS分别为64±6、57±6、48±6、45±5,1、3、5周SAS和SDS与B组对比差异有统计学意义(P<0.05)。结论对冠状动脉支架植入术后抑郁障碍患者,治疗给予常规用药的同时,积极应用抗抑郁治疗加心理干预能明显改善患者负性情绪,提高患者生活质量。
Objective To explore the role of psychological intervention in the treatment of depressive disorder after coronary stent implantation. Methods Patients with coronary artery stenting who met the diagnostic criteria were randomly divided into study group (group A) and control group (group B), and were assessed by SAS and SDS Anxiety and depression levels were measured at different time points and compared between the two groups. Results There was no significant difference in psychological behavior intervention and drug treatment between group A, SAS and SDS 63 ± 7,64 ± 6, group B 63 ± 8,65 ± 7 and group 2 (P> 0.05). After psychological intervention and medication, the scores of SAS at 8h, 1,3,5 weeks after operation in group A were 63 ± 7, 52 ± 5, 48 ± 6 and 44 ± 4, respectively. The SDS scores were 64 ± 6 and 57 ± 6 , 48 ± 6,45 ± 5,1,3,5 weeks SAS and SDS and B group, the difference was statistically significant (P <0.05). Conclusions In the treatment of patients with depressive disorder after coronary stent implantation, the positive antidepressant therapy plus psychological intervention can significantly improve the negative emotions and improve the quality of life of the patients.