低分子肝素(LMWH)由普通肝素(U FH)酶解或化学降解的方法而得其相对分子质量为2 000~10 000 D a,平均为5 000D a左右的混合物。LMWH与U FH相比具有皮下注射吸收好、半衰期长、生物利用度高、同质性较好、抗凝作用大致相同或更优、抗血栓作用强、副反应少、不需实验室监测等优势 Low Molecular Weight Heparin (LMWH) is obtained by the enzymatic or chemical degradation of Unfractionated Heparin (U FH) resulting in a mixture with a relative molecular mass of about 2 000 to 10 000 Da, averaging about 5 000 Da. Compared with U FH, LMWH has good subcutaneous injection, long half-life, high bioavailability, good homogeneity, roughly the same or better anticoagulant effect, strong antithrombotic effect, less side effects and no laboratory monitoring Advantage