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目的 :评价糖肾康胶囊治疗糖尿病肾病的疗效。方法 :对 3 0 0例糖尿病肾病患者随机分组 ,用糖肾康胶囊治疗患者 2 0 0例 ,并用卡托普利治疗 1 0 0例进行对照。结果 ,糖肾康胶囊治疗有效率与对照组相比有显著差异 (P <0 0 5)。动物实验结果表明 :糖肾康胶囊对糖尿病家兔有降糖作用 ;可明显提高大鼠糖耐量 ;对肾病大鼠尿蛋白有降低作用 ;糖肾康胶囊大剂量吸用无明显毒副作用。结论 :中药糖肾康胶囊在缓解症状、减少尿蛋白、稳定血糖方面效果良好。
Objective: To evaluate the curative effect of Tang Shen Kang capsule on diabetic nephropathy. Methods: A total of 300 patients with diabetic nephropathy were randomly divided into two groups: 200 patients were treated with Tangshen Kang Capsule, and 100 patients were treated with captopril. The results showed that there was a significant difference in the effective rate of Tang Shen Kang Capsule compared with the control group (P < 0.05). The results of animal experiments showed that: Tangshen-Kang capsule has a hypoglycemic effect on diabetic rabbits; it can significantly improve the rat’s glucose tolerance; it can reduce the urinary protein in rats with nephropathy; Tangshen-Kang capsules have no obvious toxic and side effects. Conclusion: The traditional Chinese medicine Tangshenkang Capsule has a good effect in relieving symptoms, reducing urine protein and stabilizing blood sugar.