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[目的]通过对正己烷作业工人的情感状态和神经行为功能的调查,探讨正已烷对作业工人周围神经早期损伤的指标。[方法]采用WHO推荐的神经行为核心测试组合(NCTB)和SCL-90症状自评量表,对82名正己烷作业工人进行神经行为功能和情感状态测试;用气相色谱氢火焰离子化法测定作业工人尿中2,5-己二酮浓度。[结果]在进行两组相关调查测试指标的比较中,情感状态测试接触组的总分(t=2.60,P﹤0.05)、阳性症状得分(t=2.76,P﹤0.01)和躯体化(t=3.70,P﹤0.01)、抑郁(t=2.84,P﹤0.01)、焦虑(t=2.55,P﹤0.05)等因子得分高于对照组;与全国常模比较,接触组躯体化(t=5.36,P﹤0.01)、焦虑(t=4.02,P﹤0.01)、抑郁(t=2.03,P﹤0.05)等因子得分高于全国常模;在神经行为功能测试中接触组的平均反应时(t=5.16,P﹤0.01)、手提转捷度的利手(t=3.91,P﹤0.01)和非利手(t=2.31,P﹤0.05)、目标追踪测试的正确打点数(t=2.30,P﹤0.05)和错误打点数(t=2.80,P﹤0.01)及总和(t=2.11,P﹤0.05)等测试结果与对照组比较差异具有统计学意义。[结论]正己烷对作业工人的情感状态和周围神经行为功能可能产生一定的影响。
[Objective] To investigate the effect of n-hexane on early injury of peripheral nerves of workers by investigating the emotional state and neurobehavioral function of n-hexane workers. [Methods] 82 n-hexane workers were tested for neurobehavioral function and emotional status by using the NCTB and SCL-90 Symptom Checklist 90 (WHO). The plasma samples were determined by gas chromatography with flame ionization Urine worker 2,5-hexadione concentration. [Results] The scores of positive symptom scores (t = 2.76, P <0.01) and somatization (t = 2.60, P < = 3.70, P <0.01), depression (t = 2.84, P <0.01) and anxiety (t = 2.55, P <0.05) higher than the control group. Compared with the national norm, 5.36, P <0.01). The scores of anxiety (t = 4.02, P <0.01) and depression (t = 2.03, P <0.05) were higher than those of the national norm. In the neurobehavioral function test, (t = 2.31, P <0.05), the number of correct tracking points in the target tracking test (t = 2.36, P <0.01) (T = 2.80, P <0.01) and the sum (t = 2.11, P <0.05) of the test results compared with the control group, the difference was statistically significant. [Conclusion] n-Hexane may affect workers’ emotional status and peripheral nerve function.