乙酰螺旋霉素系大环内酯类抗生素,口服后即脱乙酰基而显示抗菌作用,主要抗革兰阳性菌及某些革兰阴性球菌,临床应用较广。文献报道其口服偶有轻微胃肠不适,药物过敏罕见。现将笔者遇到的1例因口服乙酰螺旋霉素致过敏性休克报道如下。1　病例介绍　　患者男性,28岁,因鼻梁、头部 Acetylspiramycin is a macrolide antibiotic that is deacetylated to show antibacterial activity after oral administration, mainly against Gram-positive bacteria and some Gram-negative cocci, and has a wide range of clinical applications. Literature reported occasional mild oral gastrointestinal discomfort, drug allergy rare. Now I encountered in 1 case due to oral acetylspiramycin induced anaphylactic shock are reported below. 1 case description Male patient, 28 years old, due to the nose, head