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目的观察美施康定联合大黄胶囊治疗中重度癌性疼痛的临床效果。方法选择2010年2月-2012年2月间我院收治的51例中重度癌性疼痛的恶性肿瘤患者作为研究组,选择同期收治同症患者50例作为对照组,对照组给予美施康定进行治疗,研究组在对照组基础上给予大黄胶囊进行治疗,1个疗程后观察两组患者癌性疼痛的止痛效果及不良反应。结果研究组的止痛显效率为92.16%,明显高于对照组的80%,P<0.05。研究组在腹胀、便秘及恶心呕吐不良反应发生例数明显少于对照组,P<0.05,结论美施康定与大黄胶囊联合治疗中重度癌性疼痛,效果显著,可有效减少美施康定所引起的不良反应,安全可靠,值得临床推广应用。
Objective To observe the clinical effect of Meishi Kangding combined with rhubarb capsule in the treatment of moderate-severe cancer pain. Methods Fifty-one patients with malignant tumor of moderate to severe cancer who were treated in our hospital from February 2010 to February 2012 were selected as the study group and 50 patients with the same disease were selected as the control group. The control group was administered with mesylate Treatment, the research group was given rhubarb capsules on the basis of the control group for treatment, after a course of treatment to observe the analgesic effect and adverse reactions of two groups of patients with cancer pain. Results The pain relief rate of the study group was 92.16%, significantly higher than that of the control group (80%, P <0.05). The incidence of abdominal distension, constipation and nausea and vomiting in the study group was significantly less than that in the control group (P <0.05) .Conclusion Meishi Kangding combined with rhubarb capsule in the treatment of moderate and severe cancerous pain has significant effect and can effectively reduce the amount of Adverse reactions, safe and reliable, it is worth clinical application.