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目的：考察复方感冒透皮贴剂的药效作用。方法：通过小鼠热板法和醋酸扭体法观察复方感冒透皮贴剂的镇痛作用；通过大鼠酵母致热实验观察其解热作用；通过小鼠腹腔注射醋酸所致毛细血管通透性观察其抗炎作用。结果：复方感冒透皮贴剂能明显抑制热板和醋酸所致的小鼠疼痛，减少小鼠疼痛反应和扭体次数；能明显抑制干酵母所致大鼠体温升高；能明显的抑制醋酸所致毛细血管通透性的增加。结论：本实验所用复方感冒透皮贴剂具有较好的镇痛、解热和抗炎功效。“,”Objective: To observe the pharmacodynamic effects of Compound Cold Transdermal Patch (CCTP). Methods:Analgesia action was investigated with hot plate test and acetic acid writhing test in mouse; antipyretic action was evaluated antipyretic test induced by Yeast with rats; anti-inflammatory action was observed on the capillary permeability method of mouse induced by acetic acid. Results: CCTP could increase the analgesia effect with hot plate method and stretching method, delay the latency response, decrease the raised body temperature of rats and inhibit significantly capillary permeability aug-mentation caused by acetic acid in mice. Conclusions: CCTP has evident effects of analgesia, antipyretic and Anti-inflamma-tion.