2型糖尿病(T2DM)是由于胰岛功能进行性衰退,包括β细胞胰岛素分泌缺陷和α细胞胰高血糖素分泌增加造成的胰岛素与胰高血糖素比例失调[1]。最新调查统计,我国2型糖尿病发病率达到11.6%,约1.139亿人[2],而糖尿病前期的比例更高达15.5%[3]。在2型糖尿病患者中,由于胰岛素的生物调节作用发生障碍,常伴有脂质代谢的紊乱,出现脂质代谢异常,这是引起心血管并发症发生率增加的重要因素,因此在临 Type 2 diabetes (T2DM) is due to a progressive decline in pancreatic islet function, including an imbalance of insulin and glucagon caused by a deficiency in beta cell insulin secretion and an increase in alpha cell glucagon secretion [1]. According to the latest statistics, the incidence of type 2 diabetes in China reaches 11.6%, accounting for about 113.9 million [2], while the proportion of pre-diabetes is as high as 15.5% [3]. In patients with type 2 diabetes due to the biological regulation of insulin disorders, often accompanied by lipid metabolism disorder, lipid metabolism, which is an important factor in the increased incidence of cardiovascular complications, so in