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目的观察大剂量纳洛酮联合醒脑静治疗重度急性酒精中毒的效果。方法将86例重度急性酒精中毒患者随机分为治疗组和对照组。治疗组常规基础治疗加大剂量纳洛酮联合醒脑静治疗;对照组仅常规基础治疗加大剂量纳洛酮。对比观察2组清醒时间及酒后症状,分析患者临床舒适度。结果治疗组患者清醒时间短于对照组,临床舒适度优于对照组(P<0.05)。结论大剂量纳洛酮联合醒脑静救治重度急性酒精中毒疗效显著,具有较好效果。在迅速促醒的同时有效改善了酒精中毒相关症状,临床舒适度提高,使患者高质量苏醒。
Objective To observe the effect of high-dose naloxone and xingnaojing on severe acute alcoholism. Methods Eighty-six patients with severe acute alcoholism were randomly divided into treatment group and control group. Treatment group conventional basic treatment to increase the dose of naloxone combined with Xingnaojing treatment; control group only conventional basic treatment to increase the dose of naloxone. Comparative observation of two groups of awake time and symptoms of alcohol, analysis of clinical comfort. Results The awake time of the treatment group was shorter than that of the control group, and the clinical comfort was better than that of the control group (P <0.05). Conclusion High-dose naloxone combined with xingnaojing is effective in treating severe acute alcoholism. In the prompt promotion of the same time effectively improve the symptoms associated with alcoholism, improve clinical comfort, so that patients with high quality wake up.