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目的分析沈阳市区汉族尿石症(US)患者结石化学结构成分特点。方法 335例汉族US患者,经手术、自排、体外震波碎石等途径取得尿路结石标本,使用点滴反应化学试剂法测定尿石化学结构成份。同时比较上尿路US患者与下尿路US患者化学成分的差异。结果沈阳市区335例汉族US患者结石标本成分中,混合性结石210例(62.69%),单纯性结石125例(37.31%)。从结石化学成分来看,分布前五位为:草酸钙+磷酸钙145例(43.28%)、草酸钙+尿酸盐54例(16.12%)、草酸钙43例(12.84%)、碳酸磷灰石35例(10.45%)、碳酸钙21例(6.27%)。上尿路US组草酸钙+磷酸钙及草酸钙例数均明显多于下尿路US组,差异有统计学意义(P<0.05)。结论沈阳市区汉族US患者结石成分以含草酸钙混合其他复合成分为主。
Objective To analyze the chemical composition of calculi in patients with urolithiasis in the urban area of Shenyang City. Methods A total of 335 Chinese Han patients with urolithiasis were obtained by surgery, self-draining and extracorporeal shock wave lithotripsy. The chemical composition of urinary stones was determined by using the drip-reaction chemical reagent method. At the same time, we compared the chemical composition of US patients in upper urinary tract with those in lower urinary tract. Results Among the 335 Chinese Han patients with stone in Shenyang, 210 cases (62.69%) had mixed stones and 125 cases (37.31%) had simple stones. From the chemical composition of stones, the distribution of the top five were 145 cases (43.28%) of calcium oxalate and calcium phosphate, 54 cases (16.12%) of calcium oxalate and urate, 43 cases of calcium oxalate (12.84%), 35 cases of stone (10.45%), 21 cases of calcium carbonate (6.27%). The numbers of calcium oxalate, calcium phosphate and calcium oxalate in the upper urinary tract were significantly higher in the US group than those in the lower urinary tract US group (P <0.05). Conclusions The stone composition of US patients in Han nationality in Shenyang city is dominated by the mixture containing other components of calcium oxalate.