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感染是急性白血病过程中的常见并发症,也是引起死亡的主要原因之一。我院从1959年至1972年的217例急性白血病中,132例(60.8%)的致死原因是感染。近年来,由于急性白血病在化疗方面取得了重大的进展,感染的预防和处理更成为提高该病缓解率和延长缓解期的一个突出问题。现综合部分国外资料如下。发生率 Viola于1967年分析了70例急性白血病的死亡原因,感染占37~40%,出血占27~36%。Schimpff等于1972年报告48例急性非淋巴细胞性白血病,发生感染111次,其中40次伴菌血症。在30个月中有43例死亡,70%(30例)死于感染。Levine等在1972年分析了450例急性白血病(包括少数再生障碍性贫
Infection is a common complication of acute leukemia and one of the major causes of death. Of the 217 acute leukemia cases in our hospital from 1959 to 1972, 132 (60.8%) died of infection. In recent years, due to the significant progress made in the chemotherapy of acute leukemia, the prevention and treatment of infection has become a prominent problem of improving the remission rate and prolonging the remission period of the disease. Now part of the foreign information is as follows. The incidence of Viola in 1967 analyzed the causes of death in 70 cases of acute leukemia, infection accounted for 37 to 40%, bleeding accounted for 27 to 36%. Schimpff equal to 1972 reported 48 cases of acute non-lymphocytic leukemia, infection occurred 111 times, of which 40 times with bacteremia. In 30 months, 43 died and 70% (30) died of infection. In 1972, Levine et al. Analyzed 450 acute leukemias (including a minority of aplastic anemia