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早期食管癌尽管手术治疗效果甚好,但少数患者仍可复发(约占9.6%)。如果我们能在术前确定恶性肿瘤的预后,就能拟定相应的治疗措施。本文作者应用细胞分光光度计检测35例食管粘膜内和粘膜下癌细胞的DNA 含量,并对其与预后的关系加以探讨.病例与方法:本组病例均经病理证实。每例连续切片2张,一张用HE 染色,一张用Feulgen 染色。用两个波长法和细胞分光光度计检测Feulgen 染色片的癌细胞内的DNA 含量。每例DNA 含量均以100个癌细胞为计。同时检测25例癌间质的淋巴细胞的DNA 含量。求其平均值。作者根据癌细胞的DNA 含
Although early surgical treatment of esophageal cancer is very effective, a small number of patients can still relapse (about 9.6%). If we can determine the prognosis of malignant tumors before surgery, we can formulate appropriate treatment measures. The authors used cell spectrophotometer to detect 35 cases of esophageal mucosal and submucosal cancer cell DNA content, and its relationship with the prognosis to be discussed. Cases and Methods: This group of cases were confirmed by pathology. Each case was serially sectioned, one of which was stained with HE and one stained with Feulgen. The two-wavelength method and the cell spectrophotometer were used to examine the DNA content in the cancer cells of the Feulgen stained slides. The DNA content of each case is based on 100 cancer cells. At the same time, the DNA content of 25 lymphocytes of cancerous stroma was detected. Find the average. According to the DNA of cancer cells