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目的研究捐献单采血小板对红细胞参数偏高献血者血常规的影响。方法通过专业征询和体格检查的志愿无偿献血者根据血常规结果分成2组:RBC(5.5-6.5)×1012/L和/或Hb含量(160-175)g/L的实验组和一般献血者的对照组。对比捐献单采血小板前后实验组与对照组的血常规参数及单采14 d后2组血常规恢复情况。监测红细胞参数偏高者长期多次单采前后血常规,观察长期多次单采对他们血常规的影响。结果单采前实验组的RBC为(5.95±0.59)×1012/L,Hb含量为(166±10.44)g/L高于对照组的(4.94±0.38)×1012/L和(133.30±13.80)g/L;实验组的MCV为(75.62±5.35)f L低于对照组的(80.72±5.40)f L,差异均具有统计学意义(P<0.05)。但Plt计数,实验组为(272.83±49.95)×109/L,对照组为(267.30±52.81)×109/L,差异没有统计学意义(P>0.05)。其余参数如WBC、HCT、MPV等差异没有统计学意义。单采后实验组RBC为(5.24±0.78)×1012/L和Hb含量为(148±11.79)g/L仍高于对照组的(4.11±0.64)×1012/L和(115.80±17.40)g/L,实验组MCV为(74.87±5.01)f L仍低于对照组的(78.93±5.76)f L,差异有统计学意义。但Plt、WBC等其余参数两组差异没有统计学意义,说明红细胞参数偏高不影响血小板计数和采集。长期多次单采后,红细胞参数偏高献血者血常规各参数保持稳定,可以在短时间内恢复到采前水平。结论捐献单采血小板对红细胞参数偏高者的血常规参数无明显不良影响。
Objective To study the influence of donated apheresis platelets on blood routine of donors with high erythrocyte parameters. Methods Voluntary unpaid blood donors through professional consultation and physical examination were divided into 2 groups according to the blood routine results: experimental group with RBC (5.5-6.5) × 1012 / L and / or Hb content (160-175) g / L and general blood donors Control group. The blood parameters of experimental group and control group before and after the donation of apheresis plate were compared with those of the two groups after 14 days of apheresis. Long-term monitoring of erythrocyte parameters in patients with multiple long-term single blood before and after the routine observation of long-term repeated apheresis to their blood routine. Results The RBC was (5.95 ± 0.59) × 1012 / L and the Hb content was (166 ± 10.44) g / L higher than that of the control group (4.94 ± 0.38) × 1012 / L and (133.30 ± 13.80) g / L. The MCV of the experimental group was (75.62 ± 5.35) f L lower than that of the control group (80.72 ± 5.40) f L, the differences were statistically significant (P <0.05). However, the count of Plt was (272.83 ± 49.95) × 109 / L in experimental group and (267.30 ± 52.81) × 109 / L in control group, with no significant difference (P> 0.05). Other parameters such as WBC, HCT, MPV and other differences were not statistically significant. The post-harvest post-harvest RBC was (5.24 ± 0.78) × 1012 / L and the Hb content was (148 ± 11.79) g / L higher than that of the control group (4.11 ± 0.64) × 1012 / L and (115.80 ± 17.40) g / L, the experimental group MCV (74.87 ± 5.01) f L is still lower than the control group (78.93 ± 5.76) f L, the difference was statistically significant. But Plt, WBC and other parameters between the two groups was no significant difference, indicating that high parameters of red blood cells does not affect the platelet count and collection. After repeated long-term single-harvesting, the parameters of red blood cells are high, blood parameters of blood donors are stable, and can be recovered to the pre-harvest level in a short time. Conclusion Donor platelets have no significant adverse effect on blood parameters of patients with higher erythrocyte parameters.