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目的分析米非司酮配伍米索前列醇终止10~14周妊娠的引产效果,用以指导临床引产。方法选取自愿终止10~14周妊娠的孕妇112例,随机分为观察组及对照组各56例,观察组口服米非司酮及米索前列醇终止妊娠,而对照组采用雷佛奴尔注射液终止,对两组疗效及引产情况比较观察。结果观察组显效34例(60.71%),总有效率91.07%;对照组显效22例(39.29%),总有效率71.43%,观察组明显优于对照组,引产情况也显示观察组更优,统计学处理后有显著性差异(P<0.05)。结论应用米非司酮配伍米索前列醇终止10~14周孕妇妊娠,可有效减少引产时间,降低出血量,减轻患者引产痛苦,同时不存在明显不良反应,提高患者预后生活质量,在临床上的效果和作用显著,值得推广应用。
Objective To analyze the effect of mifepristone and misoprostol to terminate the induction of labor in 10-14 weeks of gestation to guide clinical induction of labor. Methods One hundred and twelve pregnant women who voluntarily terminated the pregnancy of 10-14 weeks were randomly divided into observation group and control group (n = 56). Mifepristone and misoprostol were given to the observation group to terminate the pregnancy while the control group Liquid termination, the two groups of curative effect and induction of labor were observed. Results The observation group was significantly improved in 34 cases (60.71%), the total effective rate was 91.07%. The control group was significantly improved in 22 cases (39.29%), the total effective rate was 71.43%. The observation group was significantly better than the control group, Statistical analysis showed significant difference (P <0.05). Conclusion Mifepristone combined with misoprostol to terminate 10 to 14 weeks of pregnant women can reduce the induction of labor effectively, reduce the amount of bleeding, reduce the pain induced by labor, and there is no obvious adverse reactions to improve the quality of life of patients with prognosis in the clinical The effect and role of significant, it is worth promoting application.