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目的探讨厄贝沙坦在老年原发性高血压病中的应用效果。方法将我院2008年6月至2009年6月收治的100例老年原发性高血压患者随机分为观察组60例和对照组40例,两组均采用氢氯噻嗪治疗,其中对照组加用依那普利,观察组加用厄贝沙坦,两组均以8周为一个疗程。比较两组患者的临床疗效及不良反应。结果两组患者治疗后的血压和心率亦无显著性差异,P>0.05。观察组的总有效率与对照组的总有效率无显著性差异,P>0.05。但观察组的不良反应显著少于对照组,P<0.05。结论厄贝沙坦治疗老年原发性高血压病疗效较好,且不良反应小,值得临床推广。
Objective To investigate the effect of irbesartan in elderly patients with essential hypertension. Methods 100 elderly patients with essential hypertension admitted from June 2008 to June 2009 in our hospital were randomly divided into observation group (60 cases) and control group (40 cases), both groups were treated with hydrochlorothiazide, and the control group Napril, the observation group plus irbesartan, both groups were 8 weeks for a course of treatment. The clinical efficacy and adverse reactions of the two groups were compared. Results After treatment, there was no significant difference in blood pressure and heart rate between the two groups (P> 0.05). There was no significant difference in the total effective rate between the observation group and the control group (P> 0.05). However, adverse reactions in the observation group were significantly less than those in the control group, P <0.05. Conclusion Irbesartan treatment of elderly essential hypertension better efficacy, and adverse reactions small, worthy of clinical promotion.