“404”代血浆(5％羧甲基淀粉钠注射液)作为一种新型代血浆用于临床已有近20余年的历史。1983年作者在实验工作中发现它对狗血白细胞和血小板有较好的分离作用。“404”与EDTA(或肝素、ACD液)抗凝血剂以1∶1.5的比例混合后,室温下静置15～20分钟,在179次近45升血液的应用分离中,白细胞、血小板分离率分别为93.1％和84.6％。下沉红细胞中白细 “404” on behalf of the plasma (5% sodium carboxymethyl starch injection) as a new generation of plasma for clinical use for nearly 20 years of history. In 1983, the author found that it has a good separation effect on dog white blood cells and platelets in experimental work. After “404” is mixed with EDTA (or heparin, ACD solution) anticoagulant in a ratio of 1: 1.5, it is allowed to stand at room temperature for 15 to 20 minutes. In 179 applications of nearly 45 liters of blood, white blood cells and platelets are separated The rates were 93.1% and 84.6% respectively. Sunken white blood cells in the red