胎儿宫内发育迟缓 (intrauterine growth retardation,IUGR)不但引起围产儿高死亡率 ,而且即使胎儿存活 ,在儿童期也可出现智力和躯体发育障碍 ,因此预防和减轻 IUGR的研究日益受到人们的重视。妊高征是 IUGR的原因之一 ,有研究报道血管内皮细胞损伤是妊高征的重要发病机制 ,孕 Intrauterine growth retardation (IUGR) not only causes high perinatal mortality, but even if the fetus survives, mental and physical development may also occur in childhood. Therefore, the research of preventing and reducing IUGR has received more and more attention. PIH is one of the causes of IUGR, studies have reported that vascular endothelial cell injury is an important pathogenesis of pregnancy induced hypertension, pregnancy