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用放射免疫分析法测定了４６例骨骼疾病患者血清骨钙素含量，并与其中部分病例的骨矿含量、血清碱性磷酸酶、钙、磷等指标进行了比较，结果提示３２例原发性骨质疏松症患者和７例原发性甲状旁腺机能亢进患者血清ＢＧＰ均明显高于对照组（Ｐ＜０．０１），２例慢性肾衰患者的ＢＧＰ也高于正常组（Ｐ＜０．０５）；骨矿含量测定对诊断骨质疏松症等骨病有一定的参考价值。
Radioimmunoassay was used to determine the serum levels of osteocalcin in 46 cases of skeletal diseases and compared with the bone mineral content, serum alkaline phosphatase, calcium and phosphorus in some cases. The results showed that 32 cases of primary osteoarthritis Serum BGP in patients with osteoporosis and in 7 patients with primary hyperparathyroidism were significantly higher than those in the control group (P <0.01), BGP was also higher in the 2 patients with chronic renal failure than in the normal group (P <0 .05); Determination of bone mineral content for the diagnosis of osteoporosis and other bone diseases have a certain reference value.