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目的了解影响耐多药结核病患者规律服药依从性的相关因素,探讨改进服药督导方法及措施。方法采用自行设计的患者用药依从性问卷,对78例耐多药结核病患者的用药依从性进行干预调查,发出78份问卷,回收78份问卷,有效问卷78份。将患者按登记号随机分为对照组和实验组(各39例),实验组平均年龄为(34.6±14.5)岁,对照组平均年龄为(35.3±14.7)岁,对照组采取常规用药督导模式,实验组在常规用药督导基础上采取层级管理督导。结果实验组耐多药结核病患者的完全遵照医嘱(简称“遵医”)的例数为28例,高于对照组的19例;实验组的不遵医例数为4例,少于对照组的11例,两组总体的遵医程度差异有统计学意义(Z=-2.234,P<0.05)。结论针对患者不同社会情况以及在治疗期间出现的不良反应、心理状况等,制定不同的护理干预措施,可提高患者的规律服药依从性,从而提高耐多药患者的治愈率。
Objective To understand the factors influencing the compliance of regular medication in patients with multidrug-resistant tuberculosis and to explore ways and measures to improve medication supervision. Methods A self-designed medication adherence questionnaire was used to investigate the medication adherence of 78 MDR-TB patients. 78 questionnaires were issued, 78 questionnaires were returned, and 78 valid questionnaires were collected. The patients were randomly divided into control group and experimental group (39 cases each) according to the registration number. The average age of the experimental group was (34.6 ± 14.5) years old, while the control group was (35.3 ± 14.7) years old. The control group took the conventional medication supervision mode , Experimental group in the conventional medication supervision based on the level of management supervision. Results The number of patients with MDR-TB patients in the experimental group was 28 (19), which was higher than that of the control group (4 patients), less than The control group of 11 cases, the two groups overall compliance degree was statistically significant (Z = -2.234, P <0.05). Conclusions Different nursing interventions can be taken according to the different social conditions of patients and the adverse reactions and psychological conditions during the treatment, which can improve the regular compliance of patients and improve the cure rate of MDR patients.