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目的通过对血小板及子宫动脉多普勒检测异常的分析,提供妊娠高血压综合征(妊高症)严重程度临床提示指标,探讨血小板降低与子宫动脉S/D值之间的关系。方法设妊娠高血压重度组、中度组,正常妊娠组为对照组。比较三组间的血小板参数,子宫动脉多普勒参数异同,探讨血小板与子宫动脉S/D值的关系。结果 (1)重度妊高症组血小板数与中度组比较差异有统计学意义(P<0.05)。两组妊高症组MPV值增加与对照组比较差异有统计学意义(P<0.05)。(2)重度妊高症组子宫动脉S/D值、PI、舒张早期切迹与中度妊高症组比较差异有统计学意义(P<0.05);重度、中度妊高症组RI与对照组比较差异均有统计学意义(P<0.05)。(3)重度妊高症组血小板计数与子宫动脉S/D值成反比,而中度妊高症与子宫动脉S/D值成正比。结论临床中血小板降低与子宫动脉异常反映妊娠高血压严重程度,有临床应用价值。
Objective To analyze the abnormality of platelet and uterine artery Doppler detection and to provide clinical clue indicators of the severity of pregnancy induced hypertension (PIH) and to explore the relationship between thrombocytopenia and uterine artery S / D. Methods The severe pregnancy-induced hypertension group, moderate group, normal pregnancy group as the control group. Comparison of platelet parameters among the three groups, uterine artery Doppler parameters similarities and differences, to explore the platelet and uterine artery S / D value. Results (1) There was significant difference in platelet count between severe PIH group and moderate PIH group (P <0.05). Two groups of pregnancy-induced hypertension group MPV value increased compared with the control group, the difference was statistically significant (P <0.05). (2) There was significant difference in S / D value, PI, early diastolic notch of uterine artery in severe PIH group and moderate PIH group (P <0.05). RI in severe and moderate PIH group The difference between the control group was statistically significant (P <0.05). (3) The platelet counts in severe PIH group were inversely correlated with the S / D values of uterine artery, whereas the moderate PIH was positively correlated with the S / D ratio of uterine artery. Conclusion Clinical platelet reduction and uterine artery abnormalities reflect the severity of pregnancy-induced hypertension, and has clinical value.