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原发性肝细胞癌(以下简称肝癌)是常见的恶性肿瘤,在亚洲、非洲是男性中发病率较高的恶性肿瘤之一。早在40年代,就有人观察到一些肝炎患者最后发展到肝癌,而肝癌患者又有80％伴有肝硬化,故有“肝炎—肝硬化—肝癌”“三部曲”的构想。近年来经过不断的深入研究,对几种肝炎的了解比较清楚了,认为:甲型肝炎,炎症主要在门脉区,不累及小叶中央,不会引起慢性化,细胞培养中的甲型肝炎病毒亦不影响宿主细胞的DNA,根据甲型肝炎的大量流行病学资料,也发现它与肝癌的发生无相关性;
Primary hepatocellular carcinoma (hereinafter referred to as liver cancer) is a common malignancy, and it is one of the malignant tumors with high incidence in men in Asia and Africa. As early as in the 40s, some people observed that some patients with hepatitis eventually developed liver cancer, while 80% of patients with liver cancer had cirrhosis. Therefore, the concept of “hepatitis-cirrhosis-liver cancer” “trilogy” was considered. In recent years, after continuous in-depth research, understanding of several hepatitis is relatively clear, that: Hepatitis A, inflammation mainly in the portal area, does not affect the central lobules, will not cause chronic, hepatitis A virus in cell culture Does not affect the host cell DNA, according to a large number of epidemiological data of hepatitis A, also found that it has no correlation with the occurrence of liver cancer;