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流行病学研究表明,乙型肝炎病毒携带率与肝癌高发病密切相关。钍造影剂(一种1930～1951年使用的 X 线造影剂),已知由于二氧化钍贮存于肝组织诱发肝癌。肝组织平均剂量率是25拉德/年。在德国钍造影剂研究中,调查了注射钍造影剂后3年以上的1964名造影剂携带者的死亡原因:18%死于原发性肝癌。用3年半以上时间检查了325名钍造影剂接受者和214名对照者血清。以测定 HBsAg、抗-HBs、抗-HBc 出现的频率,和是否这些肝癌病人慢性乙型肝炎病毒(HBV)感染率较高。作者的目的
Epidemiological studies have shown that the hepatitis B virus carrier rate is closely related to the high incidence of liver cancer. A contrast agent (an X-ray contrast agent used from 1930 to 1951) is known to induce liver cancer due to the storage of ceria in liver tissue. The average liver tissue dose rate is 25 rad/year. In the germanium contrast agent study, the cause of death of 1964 contrast media carriers after more than 3 years of sputum contrast agent injection was investigated: 18% died of primary liver cancer. The sera of 325 sputum contrast media recipients and 214 controls were examined over 3 and a half years. To determine the frequency of HBsAg, anti-HBs, anti-HBc, and whether these patients with liver cancer have a higher rate of chronic hepatitis B virus (HBV) infection. The purpose of the author