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在多基因遗传病中,由遗传基础和环境因素共同作用,决定一个个体患病可能性的大小,称为易患性(liability)。易患性低,患病的可能性小;易患性高,患病的可能性大。在一定的环境条件下,易患性代表个体所积累致病基因数量的多少。人群作为一个整体对传染病的易感程度,称为人群易感性(herd susceptibility)。某人群的易感性取决于构成该人群每个个体易感状态,即人
In polygenic disease, the combination of genetic basis and environmental factors determine the probability of an individual’s illness, called liability. Low susceptibility, the possibility of illness is small; high susceptibility to illness, the possibility of illness. Under certain environmental conditions, susceptibility indicates how many pathogenic genes have accumulated in an individual. The population’s susceptibility to infectious diseases as a whole is called herd susceptibility. The susceptibility of a population depends on the predisposition of each individual that constitutes that population, ie, the person