目的探讨围产期高危因素与新生儿窒息的关系。方法对周口市中心医院近年来成功分娩的6148例活产婴儿的临床资料,进行回顾调查,调查新生儿窒息发生率,了解引起新生儿窒息围产期高危因素,并计算构成。结果剖宫产新生儿窒息发生率为12.90%,自然分娩新生儿窒息发生率为7.67%;有妊娠合并症新生儿窒息发生率为20.78%,无妊娠合并症新生儿窒息发生率为6.43%。结论围产期高危因素孕周、妊娠合并症、脐带异常、胎盘异常、羊水污染等因素与新生儿窒息发生有密切关系,在围产期对上述高危因素高度重视能减少新生儿窒息的发生。 Objective To investigate the relationship between perinatal high risk factors and neonatal asphyxia. Methods The clinical data of 6148 live births of successful delivery in Zhoukou Central Hospital in recent years were retrospectively investigated to investigate the incidence of neonatal asphyxia and to understand the risk factors of perinatal period leading to neonatal asphyxia and to calculate the composition. Results The incidence of neonatal asphyxia in cesarean section was 12.90%. The incidence of neonatal asphyxia in spontaneous childbirth was 7.67%. The incidence of asphyxia in neonates with gestational complications was 20.78%. The incidence of neonatal asphyxia in non-pregnancy complications was 6.43%. Conclusion Perinatal high risk factors such as gestational age, pregnancy complications, umbilical cord abnormalities, placental abnormalities, amniotic fluid contamination and other factors are closely related to the occurrence of neonatal asphyxia, perinatal attention to these high risk factors can reduce the incidence of neonatal asphyxia.