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目的:用Meta分析方法评估中耳癌手术切除结合放疗和单纯放疗对患者生存率的影响。方法:查询筛选合格病例对照研究文献5篇,Meta分析采用Review Manager5.0统计软件,对文献结果进行定量综合分析。结果:5项中耳癌手术结合放疗和单纯放疗对中耳癌患者生存率影响的对照研究具有同质性,可以合并结果;合并效应量的检验z=0.29,P>0.05,合并效应量OR采用固定效应模型。OR合并值为0.91[95%(0.49～1.70)],菱形分布在垂直线的两侧。结论:单纯放疗和手术结合放疗对于中耳癌治疗的生存率差别并不大。我们认为早期中耳癌的治疗应以单纯放疗为首选。
OBJECTIVE: To evaluate the effect of surgery combined with radiotherapy and radiotherapy alone on the survival rate of patients with middle ear carcinoma treated by Meta-analysis. Methods: 5 cases of qualified case-control screening were screened, and Meta-analysis was conducted using Review Manager 5.0 statistical software to quantitatively analyze the literature results. Results: The control study on the effect of 5 middle ear cancers combined with radiotherapy and radiotherapy alone on the survival rate of patients with middle ear carcinoma was homogeneous and could be combined. The test of combined effect was z = 0.29, P> 0.05. The combined effect of OR Using a fixed effect model. The combined value of OR is 0.91 [95% (0.49-1.70)] and the rhombus is distributed on both sides of the vertical line. Conclusion: The difference between the survival rates of the treatment of middle ear carcinoma with radiotherapy alone and surgery plus radiotherapy is not significant. We believe that the treatment of early middle ear cancer should be the preferred radiotherapy alone.