Mesh in the form of a midurethral sling is an acceptable and generally safe treatment option for stress urinary incontinence in patients who have failed conservative treatment options such as weight loss and pelvic floor muscle training. In patients with pelvic organ prolapse, when outcomes are measured in terms of improvement in postoperative physical exam(anatomic success), many studies have demonstrated that mesh augmented repairs are superior to prolapse repairs not using mesh(native tissue). However, from a symptomatic standpoint, the outcomes of mesh and native tissue repairs are equivalent. This means that even though the physician may see more prolapse on physical exam after native tissue repair, most patients do not perceive this as a problem because their sensation of a vaginal bulge is gone. The vaginal bulge is one of the most common complaints of a patient prior to pelvic organ prolapse repair. Based on interpretation of the available literature, it does not appear that mesh is superior to native tissue repair for anterior(cystocele) and posterior(rectocele) compartment pelvic organ prolapse repair. However, for apical repairs the native tissue repairs are more technically challenging and it appears that suspension of the apex of the vagina with mesh to the sacrum(sacrocolpopexy) may yield better outcomes. Unfortunately, like all mesh surgeries there is a significant risk of mesh complications with sacrocolpopexy. Surgeons should thoroughly counsel their patients about the permanent nature of synthetic mesh and thepotential serious complications related to its use. Mesh augmented pelvic organ prolapse repairs carry unique complications that are not present with native tissue repairs and may not provide better outcomes. Mesh in the form of a midurethral sling is an acceptable and generally safe treatment option for stress urinary incontinence in in patients who have failed conservative treatment options such as weight loss and pelvic floor muscle training. In patients with pelvic organ prolapse, when outcomes are measured in terms of improvement in postoperative physical exam (anatomic success), many studies have demonstrated that mesh augmented repairs are superior to prolapse repairs not using mesh (native tissue). However, from a symptomatic standpoint, the outcomes of mesh and native tissue repairs are equivalent This means that even though the physician may see more prolapse on physical exam after native tissue repair, most patients do not perceive this as a problem because their sensation of a vaginal bulge is gone. The vaginal bulge is one of the most common complaints of a patient prior to pelvic organ prolapse repair. Based on interpretation of the available literature, it does not appear that me However, for apical repairs the native tissue repairs are more technically challenging and it appears that suspension of the apex of the vagina with mesh to the sacrum (sacrocolpopexy) may yield better outcomes. Unfortunately, like all mesh surgeries there is a significant risk of mesh complications with sacrocolpopexy. Surgeons should thoroughly counsel their patients about the permanent nature of synthetic mesh and the potential serious complications related to its use. Mesh augmented pelvic organ prolapse repairs carry unique complications that are not present with native tissue repairs and may not provide better outcomes.