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目前许多抗病毒药物均以存在于感染细胞中和病毒复制所需的逆转录酶(RT)作为靶细胞。据体内外实验报道,针对LAV/HTLV-Ⅲ复制的抗病毒药现有六种。舒拉明(Suramin):1979发现,舒拉明具有抗逆转录酶活性及其它抗病毒作用。浓度为100mg/l 时表现有抑制LAV/HTLV-Ⅲ逆转录酶活性及H9细胞株的
At present, many antiviral drugs target cells in the presence of reverse transcriptase (RT) required for virus replication in infected cells. According to in vitro and in vivo experiments, there are six antiviral drugs that target LAV / HTLV-III replication. Suramin: 1979 found that suramin has anti-retroviral activity and other antiviral effects. Concentration of 100mg / l showed inhibition of LAV / HTLV-Ⅲ reverse transcriptase activity and H9 cell line