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目的:观察不同孕周重度子痫前期患者母婴结局,为以后的临床诊治提供参考依据。方法:选取2013年1月至2016年5月我科室诊治的60例重度子痫前期患者,对其资料进行回顾性分析,根据发病时孕周不同分组,将发病孕周≤34周,即早发型重度子痫前期者列为A组,发病孕周>34周即晚发型重度子痫前期者列为B组,分析各组患者的治疗情况、并发症及母婴结局。结果:B组产前并发症发生率低于A组,子痫、肝肾损伤、胎盘早剥、产后出血并发症发生率组间比较差异有统计学意义(P<0.05),心衰、Hellp综合征并发症发生率组间比较差异无统计学意义(P>0.05);两组孕妇均无死亡病例,分娩方式间比较差异有统计学意义(P<0.05),新生儿结局中新生儿窒息发生率比较差异有统计学意义(P<0.05),新生儿死亡率间比较差异无统计学意义(P>0.05)。结论:不同孕周重度子痫前期患者对孕妇及新生儿结局影响不同,发病孕周越早,孕妇产前并发症越多,新生儿预后越差。
Objective: To observe the maternal and infant outcomes of patients with severe preeclampsia in different gestation weeks and provide reference for clinical diagnosis and treatment. Methods: Sixty patients with severe preeclampsia who were diagnosed and treated in our department from January 2013 to May 2016 were retrospectively analyzed. According to different gestational age groups, the incidence of gestational age ≤34 weeks Hair type severe preeclampsia were classified as group A, the incidence of gestational age> 34 weeks that late-onset severe preeclampsia were classified as group B, analysis of the treatment of patients in each group, complications and maternal and infant outcomes. Results: The incidence of prenatal complications in group B was lower than that in group A (P <0.05), and the incidence of preeclampsia, liver and kidney injury, placental abruption and postpartum hemorrhage were significantly different (P <0.05) There was no significant difference in the complication rates between the two groups (P> 0.05). There were no deaths in both groups, and there was significant difference in the mode of delivery between the two groups (P <0.05). Neonatal asphyxia There was significant difference between the two groups (P <0.05). There was no significant difference in neonatal mortality rate (P> 0.05). Conclusion: The patients with severe preeclampsia in different gestational age have different effects on the outcomes of pregnant women and newborns. The earlier the gestational age is onset, the more prenatal complications are in pregnant women and the worse the prognosis is.