高血压病人,常连续多年合并应用降压药,但常常忽视它对血液和血液生成器官的影响,利尿药特别是噻嗪类引起血小板减少;α甲基多巴(MD)引起抗球蛋白反应阳性(C-oomb’s 试验),有时还引起自身免疫的溶血性贫血。噻嗪类与血小板减少近50年来,已有过噻嗪类由于血小板减少所致紫癜和骨髓毒性的报告,直至1968年有人明确指出:药物减少血小板相当普遍,口服噻嗪类的71个病人中,有19人(约26%)发生血 Hypertensive patients, often for many years combined with antihypertensive drugs, but often overlook its impact on blood and blood production organs, diuretics, especially thiazide cause thrombocytopenia; α-methyldopa (MD) caused by anti-globulin reaction Positive (C-oomb’s test), sometimes also caused by autoimmune hemolytic anemia. Thiazides and thrombocytopenia Over the past 50 years there have been reports of thiazides purpura and myelotoxicity due to thrombocytopenia until 1968 when it was explicitly stated that drug-reducing platelets are fairly common in 71 patients receiving oral thiazide , 19 (about 26%) had blood