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[会议论文] 作者：Xi Li,Defen Lu,Haibin Zhou,Fengjuan He,Changshun Shao,Yaoqin Gong,
来源：第七届中国蛋白质组学大会暨第三届国际蛋白质组学论坛 年份：2011
Cullin 4B (CUL4B) is a scaffold protein that assembles cullin-RING ubiquitin ligase (E3) complexes.Recent studies have revealed that germ-line mutations of CUL4...
[会议论文] 作者：Zhao Wei,Haiyang Guo,Zhaojian Liu,Xiyu Zhang,Qiao Liu,Yanyan Qian,Yaoqin Gong,Changshun Shao,
来源：2014全球华人遗传学大会暨全国第十三次医学遗传学学术会议 年份：2014
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Zebrafish cul4a, but not cul4b, modulates cardiac and forelimb development by upregulating tbx5a exp
[会议论文] 作者：Xiaohan Zhao,Baichun Jiang,Huili Hu,Fei Mao,Jun Mi,Zhaohui Li,Qiji Liu,Changshun Shao,Yaoqin Gong,
来源：2014全球华人遗传学大会暨全国第十三次医学遗传学学术会议 年份：2014
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[期刊论文] 作者：Guosheng Lyu,Peng Su,Xiaohe Hao,Shiming Chen,Shuai Ren,Zixiao Zhao,Yaoqin Gong,Qiao Liu,Changshun Shao,
来源：癌症生物学与医学（英文版） 年份：2021
Objective: RECQL4 (a member of the RECQ helicase family) upregulation has been reported to be associated with tumor progression in several malignancies. However...
Zebrafish cul4a, but not cul4b, modulates cardiac and forelimb development by upregulating tbx5a exp
[会议论文] 作者：Xiaohan Zhao,Baichun Jiang,Huili Hu,Fei Mao,Jun Mi,Zhaohui Li,Qiji Liu,Changshun Shao,Yaoqin Gong,
来源：2014全球华人遗传学大会暨全国第十三次医学遗传学学术会议 年份：2014
CUL4A and CUL4B are closely related cullin family members and can each assemble a CulIin-R1NG E3 ligase complex (CRL) and participate in a variety of biological processes.While the CRLs formed by the...
[会议论文] 作者：Fei Mao,Zhaohui Li,Baoyue Zhao,Pengfei Lin,Pingting Liu,Meng Zhai,Qiji Liu,Changshun Shao,Wenjie Sun,,
来源：2014全球华人遗传学大会暨全国第十三次医学遗传学学术会议 年份：2014
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[会议论文] 作者：Fei Mao,Zhaohui Li,Baoyue Zhao,Pengfei Lin,Pingting Liu,Meng Zhai,Qiji Liu,Changshun Shao,Wenjie Sun,,
来源：2014全球华人遗传学大会暨全国第十三次医学遗传学学术会议 年份：2014
While we previously reported heterozygous SLC33A1 p.Ser113Arg (c.339T＞G) mutation as the cause for SPG42, hereditary spastic paraplegia (HSP) phenotype was recently reported to be absent in heterozygo...
Antitumor effect of berberine on ovarian cancer cells via induction of DNA damage and downregulation
[会议论文] 作者：Xu,Xuebin Ding,Caibo Zhang,Bingliang Wang,Wen Jia,Qiao Liu,Xiyu Zhang,Yaoqin Gong,Zhaojian Liu,Changshun Shao,
来源：2014全球华人遗传学大会暨全国第十三次医学遗传学学术会议 年份：2014
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Antitumor effect of berberine on ovarian cancer cells via induction of DNA damage and downregulation
[会议论文] 作者：Xu,Xuebin Ding,Caibo Zhang,Bingliang Wang,Wen Jia,Qiao Liu,Xiyu Zhang,Yaoqin Gong,Zhaojian Liu,Changshun Shao,
来源：2014全球华人遗传学大会暨全国第十三次医学遗传学学术会议 年份：2014
Ovarian cancer patients usually have poor prognosis due to late diagnosis and relapse with chemoresistance.It is therefore desirable to exploit new agents and novel targets for ovarian cancer treatmen...
CRL4B interacts and coordinates with SIN3A/HDAC complex to repress CDKN1A in driving cell cycle prog
[会议论文] 作者：Fan Yang,Jupeng Yuan,Yang Yang,Liangqian Jiang,Yanyan Qian,Baichun Jiang,Yongxin Zou,Yan Wang,Changshun Shao,
来源：2014全球华人遗传学大会暨全国第十三次医学遗传学学术会议 年份：2014
...
CRL4B interacts and coordinates with SIN3A/HDAC complex to repress CDKN1A in driving cell cycle prog
[会议论文] 作者：Fan Yang,Jupeng Yuan,Yang Yang,Liangqian Jiang,Yanyan Qian,Baichun Jiang,Yongxin Zou,Yan Wang,Changshun Shao,
来源：2014全球华人遗传学大会暨全国第十三次医学遗传学学术会议 年份：2014
CUL4B, a scaffold protein that assembles CRL4B ubiquitin ligase complex, participates in the regulation of a broad spectrum of biological processes.We here demonstrated a critical role of CUL4B in dri...
[会议论文] 作者：Yongxin Zou,Baichun Jiang,Changshun Shao,Yaoqin Gong,Jun Mi,Wenxing Wang,Juanjuan Lu,Wei Zhao,Zhaojian,
来源：第十二次全国医学遗传学学术会议 年份：2013
Cullin-RING ubiquitin ligases (CRLs) participate in the regulation of diverse cellular processes including cell cycle progression.Mutations in the X-linked CUL4B, a member of the cullin family, cause...
[期刊论文] 作者：Haixia Shan,Bo Wang,Xiaodong Zhang,Hui Song,Xi Li,Yongxin Zou,Baichun Jiang,Huili Hu,Hao Dou,Changshun Shao,
来源：癌症生物学与医学（英文版） 年份：2022
Objective: Hepatitis B virus (HBV) infection is a major public health problem worldwide. However, the regulatory mechanisms underlying HBV replication remain unclear. Cullin 4B-RING ubiquitin E3 ligase (CRL4B) is involved in regulating dive......
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