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[会议论文] 作者：Guisen Zhao,
来源：全国药物化学学术会议暨第四届中英药物化学学术会议 年份：2013
Raltegravir is the first approved integrase inhibitor for the treatment of HIV.The rapid mutation of the virus has led to chemo-resistant strains and there is a medical need to develop new drugs to ov...
[会议论文] 作者：Yin Chen,Guisen Zhang,
来源：第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会 年份：2012
Currently atypical antipsychotics cause numerous side effects,such as substantial weight gain and QT interval prolongation.The discovery of multireceptor antipsychotics that are chemically different,m...
Design,Synthesis,and Structure-Activity Relationship of Novel Indole Derivatives as Potent Akt Inhib
[会议论文] 作者：Yang,Dezhi,Wang,Peng,Zhao,Guisen,
来源：中国化学会第八届有机化学学术会议暨首届重庆有机化学国际研讨会 年份：2013
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[会议论文] 作者：Wei Wang,Guisen Li,Yurong Zou,Li Wang,
来源：中华医学会肾脏病学分会2014年学术年会 年份：2014
...
[期刊论文] 作者：QIU Ming,LU Jianjun,LI Yingchun,LV Guisen,
来源：中国机械工程学报 年份：2016
With constant enlargement of the application areas of the spherical plain bearings, higher quality lubrication of the bearings is required. To solve the lubrica...
[会议论文] 作者：Xudong Cao,Yin Chen,Yu Lan,Guisen Zhang,
来源：全国药物化学学术会议暨第四届中英药物化学学术会议 年份：2013
In our previous study,coumarin derivatives showed obviously antipsychotic activity.Compound 1 possesses high affinity for dopamine D2,D3 and serotonin 5-HT1A,5-HT2A receptors,and it possesses low affi...
[期刊论文] 作者：YI Xing,LENG Yongbin,LAI Longwei,ZHANG Ning,YANG Guisen,
来源：核技术（英文版） 年份：2011
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[期刊论文] 作者：LAI Longwei,LENG Yongbin,YI Xing,YAN Yingbing,ZHANG Ning,YANG Guisen,WANG Baopeng,XIONG Yun,
来源：核技术（英文版） 年份：2011
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[期刊论文] 作者：张晓亮,吕金波,张磊,张悦泽,白凌燕,刘振华,XU Jixiang,ZHENG Guisen,YU Chunlin,,
来源：城市地质 年份：2017
对北京西山某岩溶洞穴1至4层进行了氡浓度测量,研究洞穴中氡浓度的变化特征,从时间和空间两个方面探讨其变化规律及其对人身体的危害。研究结果表明,天然溶洞在不同深度位置,...
Discovery of 4-arylthiophene-3-carboxylic acid as inhibitor of ANO1 and its effect as analgesic agen
[期刊论文] 作者：Yuxi Wang,Jian Gao,Song Zhao,Yan Song,Han Huang,Guiwang Zhu,Peili Jiao,Xiangqing Xu,Guisen Zhang,Kewei,
来源：药学学报（英文版） 年份：2021
Anoctamin 1(ANO1)is a kind of calcium-activated chloride channel involved in nerve de-polarization.ANO1 inhibitors display significant analgesic activity by the local peripheral and intrathecal administration.In this study,several thiophene......
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