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Amino acid residue E543 in JAK2 C618R is a potential therapeutic target for myeloproliferative disor
[会议论文] 作者：Qingyun Wu,Huayan Guo,Lingyu Zeng,Kailin Xu,
来源：The 35th World Congress of the International Society of Hema 年份：2014
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Amino acid residue F595 plays key role in the JAK2 V617F constitute activitation and structural stab
[会议论文] 作者：Qingyun Wu,Huayan Guo,Lingyu Zeng,Kailin Xu,
来源：The 35th World Congress of the International Society of Hema 年份：2014
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Amino acid residue F595 plays key role in the JAK2 V617F constitute activitation and structural stab
[会议论文] 作者：Qingyun Wu,Huayan Guo,Lingyu Zeng,Kailin Xu,
来源：The 35th World Congress of the International Society of Hema 年份：2014
Jak2 is a nonreceptor tyrosine kinase belonging to the Janus (Jak) family of tyrosine kinases.The JAK2 V617F mutation renders the kinase constitutively active and leads to the human myeloproliferative...
Amino acid residue E543 in JAK2 C618R is a potential therapeutic target for myeloproliferative disor
[会议论文] 作者：Qingyun Wu,Huayan Guo,Lingyu Zeng,Kailin Xu,
来源：The 35th World Congress of the International Society of Hema 年份：2014
Janus kinase 2 (JAK2) is an important mediator of cytokine receptor signaling and plays a key role in the hematopoietic and immune responses.The acquired JAK2 C618R somatic mutation is detected in a s...
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