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,A novel nitroreductase-enhanced MRI contrast agent and its potential application in bacterial imagi
[期刊论文] 作者:Yun Liu,Leilei Zhang,Marc Nazare,Qingqiang Yao,Hai-Yu Hu,
来源:药学学报(英文版) 年份:2018
Nitroreductases (NTRs) are known to be able to metabolize nitro-substituted compounds in the presence of reduced nicotinamide adenine dinucleotide (NADH) as an...
A Novel Nitroreductase-enhanced MRI Contrast Agent and its Potential Application in Bacterial Imagin
[会议论文] 作者:Yun Liu,Leilei Zhang,Marc Nazare,Qingqiang Yao,Hai-Yu Hu,
来源:中国化学会第十届全国化学生物学学术会议 年份:2017
Nitroreductases(NTRs)are present in a wide range of bacterial genera and,to a lesser extent,in eukaryotes hypoxic tumour cells and tumorous tissues,which makes it an appropriate biomarker for an imagi...
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