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Nifedipine reduces iron accumulation and dopamine neuron degeneration in the iron-overloaded substan
[会议论文] 作者：Ze-Gang MA,Jun-Xia XIE,
来源：中国神经科学学会第九届全国学术会议暨第五届会员代表大会 年份：2011
Objective To investigate whether nifedipine, a blocker of L-type calcium channels can prevent iron accumulation and dopamine neuron degeneration in the substantia nigra (SN) of acute and chronic iron-...
Myricetin attenuates MPP+-induced cytotoxicity by anti-oxidation and inhibition of MKK4 and JNK acti
[会议论文] 作者：Kai ZHANG,Ze-Gang MA,Jun WANG,Jun-Xia XIE,
来源：中国神经科学学会第九届全国学术会议暨第五届会员代表大会 年份：2011
Objective Increasing evidence suggests that oxidative stress may be implicated in the degeneration of dopaminergic neurons in Parkinsons disease (PD), and anti-oxidation has been shown to be effective...
L-type Calcium Channels are Involved in Iron-induced Neurotoxicity in Primary Cultured Ventral Mesen
[期刊论文] 作者：Yu-Yu Xu,Wen-Ping Wan,Sha Zhao,Ze-Gang Ma,
来源：神经科学通报（英文版） 年份：2020
In the present study,we investigated the mechanisms underlying the mediation of iron transport by Ltype Ca2+ channels (LTCCs) in primary cultured ventral mesencephalon (VM) neurons from rats.We found that cotreatment with 100 μtmol/L FeSO4......
[期刊论文] 作者：Han Deng,Shang Liu,Dong Pan,Yi Jia,Ze-Gang Ma,
来源：中国神经再生研究（英文版） 年份：2021
Multiple studies implicate iron accumulation in the substantia nigra in the degeneration of dopaminergic neurons in Parkinson’s disease. Indeed, slowing of iro...
[期刊论文] 作者：Ze-gang Ma,Nan Jiang,Yuan-bing Huang,Xiao-kuang Ma,Jason Brek Eaton,Ming Gao,Yong-chang Chang,Ronald,
来源：中国药理学报（英文版） 年份：2020
Cocaine is one of the most abused illicit drugs worldwide.It is well known that the dopamine (DA) transporter is its major target;but cocaine also acts on other...
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