TNBS相关论文
溃疡性结肠炎（Ulcerative colitis,UC）是一种慢性非特异性炎症肠病,主要侵害直肠、结肠黏膜及黏膜下层。针刺疗法效果明确、不良反应......
炎症性肠病（IBD）是一种慢性和复发性疾病,临床表现为反复发作的腹痛、腹泻和黏液脓血便,治疗周期长,严重影响病人生活质量。目前IBD......
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旋毛虫是一种多细胞寄生虫,引发宿主的高度免疫抑制是蠕虫侵袭与寄生的重要手段和共有特征,而旋毛虫尤以为甚。大量流行病学调查结......
目的 用葡聚糖硫酸钠(DSS)和2,4,6-三硝基苯磺酸(TNBS)构建小鼠溃疡性结肠炎模型,对比研究临床症状、结肠组织病理损伤和结肠菌群......
近年来,由于多方面因素的影响导致畜禽疾病发病率不断上升,尤其是腹泻疾病发病率极高,结肠炎作为腹泻疾病的一种给畜禽养殖生产带......
目的研究2,4,6-三硝基苯磺酸(TNBS)致肠炎大鼠的背根神经节(DRG)神经元电生理特性,为更全面地了解炎症性肠病(IBD)提供借鉴。方法 ......
AIM:To establish a rat model suitable to investigate the repetitive relapsing inflammations(RRI)characteristic to Crohn......
2,4,6-trinitrobenzene sulfonic acid-induced chronic colitis with fibrosis and modulation of TGF-β1 s
AIM:To investigate whether targeting proteasome might reverse intestinal fibrosis in rats.METHODS:Chronic colitis was in......
Ulcerative colitis(UC) is an inflammatory destructive disease of the large intestine occurred usually in the rectum and ......
目的探讨姜黄素对结肠炎小鼠脾脏树突状细胞(DC)亚群及其表面活性分子的影响。方法雄性C57小鼠40只,随机分成正常组、200 mg/kg姜......
目的观察溃结康经灌肠给药对三硝基苯磺酸(trinitrobenzene sulfonic acid,TNBS)诱导的炎症性肠病动物模型的作用,以明确溃结康对......
为了研究雷公藤多苷(TWP)对三硝基苯磺酸(TNBS)/乙醇溃疡性结肠炎(UC)大鼠TLR4/My D88非依赖信号通路的调控作用,采用了TNBS/乙醇......
芍药内酯苷为白芍中的主要活性成分。本文研究芍药内酯苷通过调节TLR4通路和Tollip表达治疗实验性溃疡性结肠炎的药效作用。应用三......
目的研究雷公藤多苷片(TWPT)对2,4,6-三硝基苯磺酸(TNBS)/乙醇溃疡性结肠炎(UC)大鼠微小RNA(mi R-146a、mi R-146b)及TLR4/My D88......
AIM To verify whether curcumin(Cur) can treat inflammatory bowel disease by regulating CD8+CD11c+ cells. METHODS We eval......
AIM:to investigate the effect of Bifidobacterium infantis(B.infantis)on the T cell subsets and in attenuating the severi......
Vitamin D deficiency has been associated with a wide range of diseases and multiple forms of cancer including breast, co......
三硝基苯磺酸是氨基酸分析常用试剂,在水溶液中它是稳定的一价阴离子。Sarantonis曾研制液膜型三硝基苯磺酸离子选择电极,间接测......
有关中华猕猴桃蛋白酶(Actinidin,EC 3,4,22,14)催化功能基团的研究表明一个游离巯基,一个组氨酸残基为酶催化活性中心必需基团;......
Expression and significance of nuclear factor κB p65 in colon tissues of rats with TNBS-induced coli
AIM: To investigate the role of NF-κB in the pathogenesis of TNBS-induced colitis in rats.METHODS: Thirty-two healthy a......
Preventive and therapeutic effects of NF-kappaB inhibitor curcumin in rats colitis induced by trinit
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AIM: To explore the possible mechanisms of curcumin in rat colitis induced by tri nitrobenzene suifonic (TNBS) acid. MET......
AIM:To study the effect of angelica sinensis polysaccharide(ASP)on immunological colon injury and its mechanisms in rat......
AIM:To investigate the regulatory effect of electroacupuncture(EA) at Zusanli (ST36) on tumor necrosis factor-alpha (TN......
Effects of low molecular weight heparin on platelet surface P-selectin expression and serum interleu
AIM:To observe the effects of low molecular weight heparin(LMWH) on platelet surface P-selectin expression and serumint......
AIM: Epidemiological and clinical reports have indicated a closerelationship between cigarette smoking and inflammatory......
AIM:To determine the changes of CD8+ T subsets especiallyCD8+CD28-T regulatory cells in rat model of experimentalcoliti......
AIM:To investigate the effects of melatonin (MT) on theexpression of inducible nitric oxide synthase (iNOS) andcyclooxy......
AIM:To study the effects of Rheum tanguticumpolysaccharide_(-1)(RTP_(-1))on ulcerative colitis in rats inducedby 2,4,6-......
目的 :探讨NF -κB在血管紧张素II介导的大鼠胰腺纤维化发生中的作用。方法 :SD大鼠 (2 0 0 -30 0g)随机分为正常组、对照组、治疗......
Role of nitric oxide in the impairment of circular muscle contractility of distended, uninflamed mid
AIM: To evaluate the role of nitric oxide (NO) in the motor disorders of the dilated uninflamed mid-colon (DUMC) from tr......
Expression and significance of nuclear factor κB p65 in colon tissues of rats with TNBS-induced coli
AIM: To investigate the role of NF-κB in the pathogenesis of TNBS-induced colitis in rats. METHODS: Thirty-two healthy ......
FOS EXPRESSION IN LUMBARSACRAL SPINAL CORD AND MEDULLA OBLONGATA INDUCED BY CHRONIC COLONIC INFLAMMA
Objective To investigate Fos expression in rat lumbarsacral spinal cord and medulla oblongata induced by chronic colonic......
AIM: To explore the changes of nuclear factor-kappa B (NF-κB) DNA-binding activity, the expression of intercellular adh......
GFAP and Fos immunoreactivity in lumbo-sacral spinal cord and medulla oblongata after chronic coloni
AIM: To investigate the response of astrocytes and neurons in rat lumbo-sacral spinal cord and medulla oblongata induced......
AIM: To investigate the influence of infliximab (Remicade) on experimental colitis produced by 2,4,6,trinitrobenzene sul......
AIM: To investigate the intestinal anti-inflammatory effect and mechanism of a probiotic Lactobacillus salivarius ssp. s......
Preventive and therapeutic effects of NF-kappaB inhibitor curcumin in rats colitis induced by trinit
AIM: To ascertain the molecule mechanism of nuclear factor-KB (NF-κB) inhibitor curcumin preventive and therapeutic eff......
克罗恩病病因不明,但有研究表明肿瘤坏死因子-α(TNF-α)在该病发病机制中占有重要地位,而沙利度胺通过加速TNF-α mRNA降解而抑制......
目的 通过观察联合应用丁酸钠(NaB)与5-氨基水杨酸(5-ASA)灌肠治疗对三硝基苯磺酸(TNBS)诱发的大鼠结肠炎三叶因子3(TFF3)、白细胞......
Interleukin-12 and Th1 immune response in Crohn’s disease: Pathogenetic relevance and therapeutic in
Crohn’s disease (CD) and ulcerative colitis (UC) are chronic inflammatory disorders of the gastrointestinal tract that ......
尽管多种机制诱导炎症性肠病(IBD)的缓解,但其高复发率仍是难题。呼吸道感染与儿童IBD的复发有关。呼吸道病毒感染后产生大量趋化......
目的 研究腹腔内注射血吸虫卵对小鼠三硝基苯磺酸(TNBS)肠炎的预防作用及对肠道上皮Toll样受体4(TLR4)表达的影响.方法 40只BALB/c......
Insights from advances in research of chemically induced experimental models of human inflammatory b
Inflammatory bowel disease(IBD),the most important being Crohn’s disease and ulcerative colitis,results from chronic dy......
AIM: To investigate the correlation between in vitro and in vivo immunomodulation potential of the probiotic strain and ......
Therapeutic and prophylactic thalidomide in TNBS-induced colitis: Synergistic effects on TNF-α, IL-1
AIM: To evaluated the therapeutic and prophylactic effect of thalidomide on 2, 4, 6-trinitrobenzene sulfonic acid (TNBS)......
Intrahepatic CD8~+ lymphocyte trapping during tolerance induction using mushroom derived formulation
AIM: To determine the immunomodulatory effect of Shiitake (a mushroom extract),we tested its effect on liver-mediated im......
