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目的 研究二氯乙酸盐(dichloroacetate,DCA)对神经胶质瘤细胞U87的生物学行为的影响及可能机制,探讨DCA与脑恶性肿瘤治疗之间的关......
目的 探讨二氯乙酸盐(dichloroacetate,DCA)在体外药敏检测实验中对非小细胞肺癌(NSCLC)脑转移瘤细胞的抑制作用.方法 使用DCA干预......
肿瘤细胞线粒体代谢途径已成为抗肿瘤的关注点.二氯醋酸钠(DCA)是作用于线粒体的小分子物质,显示出一定的抗肿瘤作用.因此,本文考......
目的 观察早期和晚期二氯乙酸盐(dichloroacetate,DCA)干预对左肺切除(pneumonectomy,PE)联合野百合碱(monocrotaline,MCT)皮下注......
目的 探讨二氯乙酸盐对肺动脉高压大鼠肺组织Kv1.5表达的影响.方法 雄性SD大鼠32只,8周龄,体重200~250 g,采用随机数字表法,将大鼠......
报道了二氯醋酸盐水溶液在不同PH柠檬酸盐溶冲液、不同浓度、不同温度情况下的稳定性,得出该盐分解按零级反应进行,其活化能为155.37KJ/mol。......
目的研究二氯醋酸钠(DCA)对大鼠在高原环境下形成高原低氧性肺动脉高压的预防作用,以及对高原低氧大鼠肺动脉平滑肌细胞(PASMCs)上电压......
目的探讨二氯乙酸对急性髓系白血病细胞株U937凋亡的影响及其相关机制。,方法急性髓系白血病细胞株U937细胞为研究对象,采用不同浓度......
目的:观察二氯乙酸钠(sodium dichloroacetate,DCA-Na)对人骨肉瘤MG63细胞增殖、凋亡和迁移的影响。方法:将对数生长期的MG63细胞随机......
PharmacokineticsofintravenouslyadministeredsodiumdichloroacetateinrabbitsGuBin(顾斌);SongLing(宋岭);JiangYongpei(蒋永培);WenAidong(文.........
目的:观察复方二氯醋酸二异丙胺联合复方甘草甜素治疗慢性乙型肝炎是否具有临床协同效应。方法:将366例慢性乙型肝炎患者随机分为治......
Sodium dichloroacetate(DCA)has been studied as a metabolic cancer therapy since 2007,based on a publication from Bonnet ......
目的:为研究Dichloroacetate(DCA)降低血乳酸的疗效。方法:采用作者改良的BarKer氏法观察正常及高乳酸血症(HLA)家兔血乳酸值在接受DCA后的动态变化。结果:静脉注射DCA(50mg/kg)后15及30min时......
目的:为研究Dichloroacetate(DCA)降低血乳酸的疗效。方法:采用作者改良的BarKer氏法观察正常及高乳酸血症(HLA)家兔血乳酸值在接受DCA后的动态变化。结果:静脉注射DCA(50mg/kg)后15及30min时......
Oral dichloroacetate sodium(DCA)has been investigated as a novel metabolic therapy for various cancers since 2007,based ......