EUKARYOTIC相关论文
Nasopharyngeal carcinoma (NPC) is one of thehighly prevalent malignancies in SoutheastAsia.1 Chemotherapy and radiothera......
真核细胞翻译起始因子4E(eukaryotic transla-tion initiation factor 4E,eIF4E)是一25kD多肽,其基因位于4q21-4q25。近来有大量报......
Both eukaryotic and prokaryotic pathogens infect the host stably via an immune evasion mechanism termed mutually exclusi......
Design,Synthesis and Antitumor Activity of Fluoroquinolone C3 Heterocyclic Bis-oxadiazole Methylsulf
To discover an efficient route for the shift from an antibacterial fluoroquinolone to an antitumor one based on the mech......
Extract from Phyllanthus urinaria L.Inhibits Hepatitis B Virus Replication and Expression in Hepatit
Objective:To explore the effects of the extract from Phyilanthus urinaria L.on hepatitis B virus(HBV) replication and ex......
RNA silencing is a conserved mechanism found ubiquitously in eukaryotic organisms.It has been used to regulate gene expr......
Antimicrobial peptides are widely distributed in nature,existing in organisms of plants,insects,and vertebrates.It has b......
Agglutinin isolated from Arisema heterophyllum Blume induces apoptosis and autophagy in A549 cells t
Arisaema heterophyllum Blume is one of the three medicinal plants known as traditional Chinese medicine Rhizoma Arisaema......
真核细胞翻译起始因子4E(eukaryotic initiation factor 4E,eIF4E)是蛋白质翻译起始的关键因子,磷酸化eIF4E(p-eIF4E)与真核生物蛋......
Screening of genes for proteins interacting with the PS1TP5 protein of hepatitis B virus:probing a h
Background The hepatitis B virus (HBV) genome includes S, C, P and X regions. The S region is divided into four subregio......
Mitochondria and lysosomes are essential cellular organelles in most eukaryotic cells by playing the physiological roles......
Protective Effects of Overexpression TCR Vβ5.2-HSP70 and TCR Vβ8.2-HSP70 against Collagen-Induced Ar
Collagen-induced arthritis(CIA)is an animal model,which closely resembles human rheumatoid arthritis(RA)in pathogenesis ......
Short Hairpin RNA-mediated MDR1 Gene Silencing Increases Apoptosis of Human Ovarian Cancer Cell Line
Objective: Recurrent ovarian cancer is often resistant to drugs such as paclitaxel. Short hairpin RNA (shRNA) targeting ......
The rapid growth of the global HIV/AIDS epidemic makes it a high priority to develop an effective vaccine.Since a live a......
Objective To observe the effects of HCV protein,NS3 and NS5A on IFN-βin HepG2 cells and its regulation mechanism.Method......
Construction of the tissue engineering seed cells(HaCaT-EGF) and analysis of its biological characte
Objective:To construct the tissue engineering seed cell(HaCaT cell line) with stable expression of the human epidermal g......
Discovery and significance of microfossils from Qinbaikouian Dazhuang Formation in Luonan, Shaanxi P
THE microfossils were obtained by using 5%—7% HF acid from Qingbaikouian Dazhuang Formation in Luonan County, Shaanxi ......
Objective To investigate the effect of plasmid pEGFP-hepatocyte growth factor (HGF)-Cl on rat acute ischemia of hindlimb......
In the eukaryotic transcriptome, both the numbers of genes and different RNA species produced by each gene contribute to......
A New Farnesyl Diphosphate Synthase Gene from Taxus media Rehder:Cloning,Characterization and Functi
Farnesyl diphosphate synthase(FPS;EC 2.5.1.10) catalyzes the production of 15-carbon farnesyl diphosphate which is a bra......
AIM:To construct human eosinophil-derived neurotoxin(hEDN) and HBV core protein (HBVc) eukaryotic fusionexpression vect......
A small yeast RNA inhibits HCV IRES mediated translation and inhibits replication of poliovirus in v
AIM:To investigate the anti-virus infection activity of internalribosome entry site (IRES) specific inhibitor RNA (IRNA......
AIM:To compare the efficiency of different plasmids asDNA vectors by cloning three HBsAg-encoded genes intotwo eukaryot......
Primary hepatocellular carcinoma (HCC) is one of the most common cancers occurring in human, and there is strong epidem......
Objective To construct p IRES2-ZsG reen1/FⅨexpression vector,using the pcDNA/FⅨplasmid containing FⅨcDNA as template,......
AIM:To investigate the effect of antisense RNA to vascularendothelial growth factor_(165)(VEGF_(165))on human esophagea......
Objective: To explore the role of vascular endothelial growth factor (VEGF) in the angiogenesis and development of human......
Telomerase plays an important role in cell proliferation and carcinogenesis and is believed to be a good target for anti......
AIM:To construct a recombined human AFP eukaryoticexpression vector for the purpose of gene therapy and targettherapy o......
AIM:To explore the influence of angiostatin up-regulationon the biologic behavior of gastric cancer cells in vitro andi......
AIM:Cancer gene therapy has received more and moreattentions in the recent decade.Various systems of genetherapy for ca......
Inhibitory effects of antisense RNA of HAb18G/CD147 on invasion of hepatocellular carcinoma cells in
AIM:To study the inhibitory effects of antisense RNA ofHAb18G/CD147 on invasion of hepatocellular carcinoma(HCC)cells i......
Apoptosis-inducing effect of recombinant Caspase-3 expressed by constructed eukaryotic vector on gas
AIM:To investigate the apoptosis-inducing effect ofCaspases-3 expressed by constructed eukaryotic vector ongastric canc......
Analysis of gene expression profile induced by EMP-1 in esophageal cancer cells using cDNA Microarra
AIM To obtain human esophageal cancer cell EC9706 stablyexpressed epithelial membrane protein-1(EMP-1)withintegrated euk......
AIM:To construct a pEgr-IFNy plasmid and to investigateits expression properties of interferon-γ(INF-γ)induced byirra......
Inhibitory effect of antisense vascular endothelial growth factor 165 eukaryotic expression vector o
AIM:To construct antisense VEGF_(165) eukaryotic expressionvector PCDNA_3-as-VEGF_(165) and to study its expression and......
AIM:To evaluate the effects of 3,3’-diethyl-9-methylthia-carbocyanine iodide (DMTCCI) on DNA primase activity and onap......
Combined gene therapy of endostatin and interleukin 12 with polyvinylpyrrolidone induces a potent an
AIM:To study the antitumor effect of combined genetherapy of endostatin and interleukin 12(IL-12)withpolyvinylpyrrolido......
AIM:To transfect murine angiostatin cDNA into humanhepatocellular carcinoma cell line SMMC-7721 and toinvestigate its e......
AIM:To construct an eukaryotic superantigen gene expressionvector containing the recombinant gene of SEA and CD80molecu......
Expression of TIMP-3 Gene by Construction of a Eukaryotic Cell Expression Vector and Its Role in Red
The present study is aimed at studying the gene for TIMP-3,a mammalian tissue inhibitor,by constructing arecombinant eu......
Two novel eukaryotic translation initiation factor 5A genes from Populus simonii × P. nigra confer t
The role of plant e IF5 A proteins in multiple biological processes, such as protein synthesis regulation,translation el......
Objective: To construct and express a humanmouse chimeric antibody against human bladder cancer. Method: The variable re......
Prophylaxis of tumor through oral administration of IL-12 GM-CSF gene carried by live attenuated sal
A live attenuated AraA autotrophic mutant of Salmonella typhimurium (SL3261) was used as carrier for eukaryotic expressi......
Expression of nuclear factor-KB in hepatocellular carcinoma and its relation with the X protein of h
AIM In this study we investigated therelationship of the X protein of HBV and nuclearfactor-κB(NF-κB)and the expressi......
Lambda-cyhalothrin disrupts the up-regulation effect of 17β-estradiol on post-synaptic density 95 pr
Lambda-cyhalothrin(LCT),one of the type II pyrethroids,has been widely used throughout the world.The estrogenic effect o......
CRISPR/Cas9 is a versatile genome-editing tool which is widely used for modifying the genome of both prokaryotic and euk......
Construction of eukaryotic expression plasmid containing HCV NS3 segment and protein expression in h
AIM:To construct the eukaryotic expression plasmidcontaining HCV NS3 segment and to analyze theexpression of NS3 protei......
AIM To compare the effects of liposomes andglyco-poly-L-lysine on liver targeted uptake andexpression of plasmid in rat......
This study aimed to develop a cell culture model of Huntington disease and observe the effect of sodium butyrate on this......
