Morriswatermaze相关论文
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Effects of peptides from Phascolosoma esculenta on spatial learning and memory via anti-oxidative ch
This study was aimed to evaluate effects of peptides from Phascolosoma esculenta and its ferrous chelate peptides on spa......
Objective Several studies have shown that housing conditions may affect ones behavior and physiology.In this study,we in......
Objective: It was reported that melamine was deliberately added to infant formula in order to increase protein content.R......
Purpose: This article is to reveal behavioral,cognitive,spontaneously epilepsy,and electroencephalographic(EEG)character......
Objective Alzheimers disease(AD)is a progressive and degenerative disorder accompanied by cognitive impairment,but effec......
The effects of Colivelin on spatial memory and hippocampal long term potentiation in APP/PS1 transge
Objective: Alzheimers disease(AD)is the most common cause of dementia....
Objective Alzheimer disease(AD)is a fatal neurodegenerative disorder characterized by progressive cognitive impairment a......
The Change of Early Cognition Function on Neonatal Ischemia-Hypoxic Brain Damage Rats and Interventi
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Objective: To explore the effects of occlusal interference on spatial learning and memory functions in rats.Methods: Six......
Objective: The present study was aimed to observe the effects of D-serine on the learning and memory functions of the MK......
Rattin protects against Aβ25-35 indued impairments in synaptic plasticity and spatial cognition of r
Rattin (RN), a humanin-like peptide, shared with Humanin ability to protect neurons against amyloid β protein (Aβ)-ind......
Extensive research has shown that the aggregation and toxicity of amyloid -beta protein (A β) are closely related to th......
Objective Amyloid β protein (Aβ) has been thought to be responsible for loss of memory in Alzheimers disease (AD).Ratt......
Objective The pharmacological effect of propolis in immune system has been well verified.But there were only few of rese......
Behavioral and electrophysiological study on the neuroprotective effects of lixisenatide against Aβ2
Although glucagon-like peptide-1 (GLP-1), an insulin-releasing gut hormone, has been thought as a promising treatment fo......
Amyloid β protein(Aβ)is the main component of extracellular senile plaques in the brain of patients with Alzheimers di......
GLP-1 analogue CJC-1131 Rescues Spatial Cognition and Synaptic Plasticity of Rats from Aβ1-42-induce
Although the amyloid β protein (Aβ) aggregated in the brain has been recognized as one of the main pathological charac......
Effect of chronic stress on extracellular levels of amino acids in the hippocampal dentate gyrus dur
As the entry point of information into the hippocampus,the hippocampal dentate gyrus(DG)encodes and processes new inform......
Object To investigate the effect of neonatal BDE-209 exposure on the expression levels of the core SNAREs(Synaptobrevin ......
Neuroplasticity mechanism for the beneficial effects of olanzapine on schizophrenia-like spatial mem
Background: Schizophrenia patients exhibit a wide range of impairments in cognitive functions.Clinically, typical antips......
Enriched environment improve the function of learning and memory after traumantic brain injury in ra
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PirB expression and glial reaction influence synaptic plasticity in the rat brain via intrahippocamp
The aim of our study is to investigate the changes in hippocampal synapses and their relation with learning-memory abili......
Aim To observe the effects of catalpol on scopolamine-induced Amnesia and cerebral infarction after focal cerebral ische......
Objective TO investigate the effects of Tao Xin Fang on the learning and memory ability,and the synapse structure and ne......
Chronic stress results in hippocampal injury, and impairs learning and memory ability of animals.However the cellular me......
Objective Al(mal)3 is a electrically neutral compound of aluminum, it can form metastable solution under pH neutral cond......
Abnormal expression of heat shock protein 27 and 70 in cortex of rats with spatial learning and memo
Objectives Manganese (Mn) is an essential nutrient but excessive exposure to Mn is neurotoxic.The mechanism of Mn neurot......
The effects of hypoxia on cognitive capability on aged mice is paid poorly attention, especially exposure to long-term h......
Ginsenoside Rg1 Attenuates Okadaic Acid Induced Spatial Memory Impairment by the GSK 3β/Tau signalin
There has been no extensive characterization of the effects of Ginsenoside Rgl,a pharmacological active component purifi......
B Vitamins Supplementation Can Improve Cognitive Functions and May Relate to the Enhancement of Tran
Objective:To determine whether B vitamin treatment was sufficient to reduce cognitive impairment associated with high-fa......
Alzheimer's disease (AD) is a chronic neurodegenerative disease. The symptoms include memory and spatial learning di±c......
Intrahippocampal injections of ritanserin (5HT2A2C antagonist) and granisetron (5HT3 antagonist) mod
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Disruption of the CaMKIICREB Signaling Is Associated with Zinc Deficiency-induced Learning and Memor
As an important region of brain,hippocampus is affected by levels of zinc ions.Many studies have shown that zinc deficie......
目的:观察单纯脑震荡及多重脑震荡对大鼠空间认知行为的远期影响.方法:7周龄SD雄性大鼠180只,体重280±30 g,随机分为实验对照组(C......
目的 探讨脑深部电刺激(DBS)伏核对吗啡成瘾依赖大鼠学习记忆的影响.方法 通过DBS电极刺激吗啡成瘾依赖大鼠双侧伏核,于吗啡注射第......
目的 探讨急性吗啡戒断诱发的条件性位置厌恶效应(CPA)与动物在空间记忆任务表现上的个体差异之间的关系.方法 30只雄性Wistar大鼠......
目的研究不同剂量锰暴露对幼鼠空间学习记忆的影响。方法刚出生的幼鼠随机分为对照组(生理盐水) 和MnCl2 10,20,30 mg/kg组。每组1窝......
目的探讨模拟单一与复合航天特因环境下大鼠在Morris水迷宫(Morris water maze,MWM)实验中的学习记忆能力差异,为建立航天特因环境下......
Basic fibroblast growth factor improves learning and memory deficits in a mouse model of vascular de
BACKGROUND:Basic fibroblast growth factor(bFGF)exhibits neuroprotective functions,but the possible mechanisms of bFGF on......
Endogenous adult neurogenesis and cognitive function recovery following traumatic brain injury in th
BACKGROUND:Endogenous neural progenitor cells play a beneficial role for cognitive recovery following traumatic brain in......
Molecular mechanisms and the role of the protein kinase pathway in rat spatial memory impairment fol
BACKGROUND:Animal experiments have demonstrated that isoflurane exposure alone induces leing and memory deficits for wee......
目的 探讨柠檬苦素(limonin)对自然衰老大鼠学习记忆能力及因衰老而导致机体氧化损伤的影响.方法 采用18月龄雄性SD大鼠作为自然衰......
目的探讨孕期补锌对胎儿生长受限(fetal growth restriction,FGR)仔鼠空间学习记忆能力的影响。方法建造SD孕鼠FGR模型,孕鼠随机分......
目的探讨体温增高对新生大鼠缺氧缺血性脑损伤(HIBD)后学习记忆功能的影响。方法新生7日龄SD大鼠62只,随机分为高温HIBD组、常温HI......
Objective:To investigate the protective effect of ultrasound-combined microbubbles on hippocampal acetylcholinesterase(A......
目的 探讨长期强迫游泳后大鼠焦虑抑郁行为以及空间学习和记忆能力的动态变化.方法 将24只成年雄性SD大鼠随机分为对照组(CONTROL......
BACKGROUND: Complex leing tasks result in a greater number of paradoxical sleep phases, which can improve memory. The ef......
BACKGROUND: Modern pharmacological studies have demonstrated that Panax notoginseng saponins (PNS) can ameliorate and pr......