isoflurane相关论文
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Effectsofdifferentconcentrationanddurationtimeofisofluraneon acuteandlong-termneurocogn
Postoperativecognitivedysfunction(POCD)isadeclineincognitiveperformanceafterasurgerywithanaesthesia.Theexact reasonsofsu......
Cumulative studies found that general anesthetics can cause acute neuroapoptosis and long-term cognitive deficit in deve......
Murine dock gene expression in the SCN and PBMCs during the daily sleep-wake rhythm and after isoflu
目的:昼夜节律主要由位于下丘脑视交叉上核(SCN)所调节的中枢生物钟系统与包括心脏、肾脏和肝脏等几乎所有组织器官的外周生物钟系......
Isoflurane Inhibits Embryonic Stem Cell and Induces Pluripotent Stem Cell Self-renewal by Down-regul
Many pregnant women are exposed to inhalation anesthetics (including isoflurane) for non-obstetric surgery1.The commonly......
TIGAR contributes to ischemic tolerance induced by cerebral preconditioning through scavenging of re
OBJECTIVE Previous study showed that TIGAR(TP53-induced glycolysis and apoptosis regulator)protected ischemic brain inju......
Post-operative cognitive dysfunction(POCD)has been widely reported,especially in elder patients.An association betweenPO......
Isoflurane relieves zymosan-induced neutrophil inflammatory response by targeting NMDA glutamate rec
Introduction: Neutrophil release of NO/ONOO- induces endothelial cell barrier dysfunction in inflammatory acute lung inj......
Female infertility after occupational exposure to inhaled anesthetic agents has attracted critical attention,but systema......
Lateral Hypothalamic Area Glutamatergic Neurons and Their Projections to the Lateral Habenula Modula
The lateral hypothalamic area(LHA)plays a pivotal role in regulating consciousness transition,in which orexinergic neuro......
Lateral Hypothalamic Area Glutamatergic Neurons and Their Projections to the Lateral Habenula Modula
The lateral hypothalamic area(LHA)plays a pivotal role in regulating consciousness transition,in which orexinergic neuro......
目的分析丙泊酚对急性颅脑损伤手术患者的脑保护作用。方法选取2014年6月至2016年6月急性颅脑损伤患者90例,随机分为两组,每组45例。......
目的 研究异氟醚麻醉对胎鼠出生后的学习记忆能力,以及对胎鼠大脑海马CA1区和皮质压部后区(Retrosplenial RS)Bcl-2/Bax表达变化的......
目的探讨c-Jun氨基末端激酶(the c-Jun N-terminal kinase ,JNK)信号通路对异氟醚诱导新生大鼠海马神经细胞凋亡以及对磷酸化JNK、B......
目的研究亚麻醉深度(0.3MAC)的异氟醚和七氟醚对新生大鼠海马齿状回神经细胞增殖以及ERK1/2蛋白磷酸化表达的不同影响。方法72只P7......
Molecular mechanisms and the role of the protein kinase pathway in rat spatial memory impairment fol
BACKGROUND:Animal experiments have demonstrated that isoflurane exposure alone induces leing and memory deficits for wee......
In vivo field recordings effectively monitor the mouse cortex and hippocampus under isoflurane anest
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Dexmedetomidine mitigates isoflurane-induced neurodegeneration in fetal rats during the second trime
Dexmedetomidine has significant neuroprotective effects. However, whether its protective effects can reduce neurotoxicit......
Inhibition of α5 GABAA receptors has preventive but not therapeutic effects on isoflurane-induced me
The α5 subunit-containing gamma-amino butyric acid type A receptors (α5 GABAARs) are a distinct subpopulation that are......
Rapid tolerance against focal cerebral ischemia induced by isoflurane anesthesia is attenuated by ad
The brief anesthesia with isoflurane induces rapid tolerance against focal cerebral ischemia in rats and adenosine A1 re......
Objective: To establish a rat model of warm partial hepatic ischemia-reperfusion (IR), and investigate the protective an......
目的:探讨不同吸入性麻醉药对小儿法洛四联症术后肝功能的影响.方法:选择在体外循环下择期行法洛四联症根治术患儿30例,随机分为3......
目的 探讨丙泊酚与异氟烷麻醉对胰岛素抵抗和促炎细胞因子的影响.方法 选择42例行择期上腹部手术患者为研究对象,采用随机数字表法......
目的 探讨丙泊酚和异氟烷对骨关节结核患者炎性作用的影响,为骨关节结核的临床治疗提供科学依据.方法 抽取2012年6月-2015年6月在......
目的 观察再灌注期腹腔注射内毒素脂多糖(LPS)对大鼠肝脏缺血/再灌注(I/R)损伤的影响以及异氟醚(ISO)预处理的干预作用.方法将32只......
目的 探讨异氟烷预处理或后处理对大鼠局灶性脑缺血/再灌注(I/R)时炎症因子、脂质过氧化等相关指标的影响.方法 将32只SD大鼠按随......
目的探讨在异氟烷麻醉总时间一致的前提下,不同麻醉时间间隔对发育期大鼠急性脑损伤后认知行为的影响。方法选用生后7 d的SD大鼠,按......
Objective:To explore effect of different anesthesia methods and different anesthetics on erythrocyte immune function in ......
Isoflurane Enhances the Expression of Cytochrome C by Facilitation of NMDA Receptor in Developing Ra
This study examined the effects of clinically relevant concentrations of isoflurane on the amplitude of NMDA receptor cu......
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目的 比较两种不同全身麻醉方法对老年高血压病患者腹腔镜胆囊切除术应激反应的影响.方法 将26例腹腔镜胆囊切除的老年高血压病患......
目的 比较七氟醚和异氟醚对肝硬化患者行肝切除术后肝功能变化的影响.方法 将40名年龄为40~70岁的肝硬化(Child-Pugh A级),择期行肝......
目的 探讨艾司洛尔复合瑞芬太尼对上腹部手术患者异氟醚MAC的影响.方法 拟在全麻下行上腹部手术患者100例,随机分为5组(n=20),麻醉......
目的 探讨异氟烷吸入复合罗哌卡因骶管阻滞在小儿腹股沟斜疝手术中的应用效果.方法 120例腹股沟斜疝患儿在腹腔镜下行鞘状突高位结......
目的 比较不同麻醉下老年高血压患者围术期心肌损伤的程度,为老年高血压患者选择适宜的麻醉方法.方法 择期行胸外科手术的老年高血......
Liver transplantation (LT) recipients are known to require less anesthetic agents. Providing minimally required anesthet......
<正> 异名 Forane,Aerrane,化合物469 化学名 1-氯-2,2,2-三氟乙基二氟甲基醚 F2CH—O—CHCI—CF3 药效分类全身麻醉药开发单位 (美......
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目的 探讨右美托咪定预处理对异氟醚引起新生大鼠脑发育毒性的保护作用及与坍塌反应调节蛋白-2的关系.方法 60只出生后7d的SD大鼠,......
Brain interstitial fluid drainage and extracellular space affected by inhalational isoflurane: in co
Brain interstitial fluid drainage and extracellular space are closely related to waste clearance from the brain.Differen......
目的:观察口服异氟烷(Iso)、七氟烷(Sev)对小鼠的镇痛及催眠等麻醉作用.方法:按分层随机设计,将180只小鼠分为18组(n=10),分别用于......
目的 观察异氟烷预处理对心脏瓣膜置换术病人血浆肌红蛋白(Mb)、血管假性血友病因子(vWF)浓度和心肌细胞显微结构的影响,以证实异......
目的异氟醚预处理能对大鼠肾脏发挥急性期缺血保护作用,但急性期保护作用仅能维持2~3h。探讨异氟醚延迟性预处理是否能减轻肾脏缺血......
目的 比较相同MAC浓度的地氟醚和异氟醚对脑电图的影响.方法 2 0例 2 0~ 5 0岁 ,ASAⅠ~Ⅱ级择期手术的病人 ,均不用术前药.麻醉诱......
,Isoflurane preconditioning protects against ischemia-reperfusion injury partly by attenuating cytoc
Aim: To examine if isoflurane preconditioning can attenuate ischemia/reperfusion injury by reducing cytochrome c release......
,Lipid metabolism disturbances and AMPK activation in prolonged propofol-sedated rabbits under mecha
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,EMLA(R) Cream coated on endotracheal tube with or without epidural lidocaine reduces isoflurane req
This study was designed to evaluate the effect of tracheal topical anesthesia using EMLA(R) Cream (EC)coated on the endo......
,Up-regulation of heme oxygenase-1 by isoflurane preconditioning during tolerance against neuronal i
Heme oxygenase (HO) is the rate-limiting enzyme in the degradation of heme to produce bile pigments and carbon monoxide.......
,Beclin1-mediated ferroptosis activation is associated with isoflurane-induced toxicity in SH-SY5Y n
The widely used inhalation anesthetic,isoflurane,potentially induces neuronal injury in clinical practice.Previous studi......