Organoids相关论文
唾液腺是口腔颌面部的重要器官，环境和遗传因素导致唾液腺肿瘤和非肿瘤性疾病的发生，但其具体发生机制，并不十分清楚，其中一个重要原因......
Valuable implement to the animal neurological models: Neurological diseases remain the largest cause of death and disabi......
Organoids are three-dimensional culture systems generated from embryonic stem cells, induced pluripotent stem cells, and......
Background::Sweat secreted by eccrine sweat glands is transported to the skin surface through the lumen. The eccrine swe......
Long Term Culture of Human Kidney Proximal Tubule Epithelial Cells Maintains Lineage Functions and S
The mechanism of how SARS-CoV-2 causes severe multi-organ failure is largely unknown.Acute kidney injury (AKI) is one of......
类器官是使用三维培养方式模拟细胞的体内生长微环境，在体外构建的具有多种细胞成分的组织模型，在疾病研究、药物筛选、胚胎发育等领......
类器官是体外由有自我更新能力的干细胞在三维支架下形成的具有特异性的微型器官。随着该细胞培养系统的发展，近年来类器官培养已逐......
AIM:To explore the temporal mitochondrial characteristics of retinal pigment epithelium(RPE)cells obtained from human em......
Raltitrexed as a synergistic hyperthermia chemotherapy drug screened in patient-derived colorectal c
Objective:Organoids have recently been used as in vitro models to screen chemotherapy drugs in combination with hyperthe......
目前对于结直肠肿瘤的实验研究主要有两种临床前模型,一种是结直肠癌细胞系(CCL)模型,另一种是患者来源的肿瘤异种移植(PDTX)模型,......
类器官是由单个干细胞、祖细胞或不同谱系的细胞簇在三维培养条件下自发形成类似体内组织结构的细胞簇.近年来,类器官技术为干细胞......
目的:随着核技术的发展与放射治疗在临床肿瘤治疗领域的广泛应用,如何有效防护急性辐射损伤已成为核安全领域的重要研究内容。本课......
In recent years,organoid technology,i.e.,in vitro three-dimensional(3D)tissue culture,has attracted increasing attention......
Error-free cell division depends on the accurate assembly of the spindle midzone from dynamic spindle microtubules to en......
Here, we describe the use of monolayers of intestinal epithelial cells derived from intestinal organoids and transcripto......
目的综述细胞治疗与组织工程方法再生涎腺的研究新进展,为治疗涎腺功能障碍提供理论依据。方法广泛查阅近年有关细胞治疗与组织工......
The intestinal epithelium is one of the most rapidly renewing tissues,which is fueled by stem cells at the base of the c......
目的探索小肠隐窝分离,小肠类器官培养、传代、冻存、复苏和蛋白提取的方法,研究R-Spondin1的浓度对小肠类器官成熟的影响。方法分......
现有的生物学方法不能证明细胞纠缠。数学模型、计算机模拟、机器学习、类器官模拟和活细胞示踪可能寻找到细胞纠缠的痕迹。数学方......
Here, we describe the use of monolayers of intestinal epithelial cells derived from intestinal organoids and transcripto......
Here, we describe the use of monolayers of intestinal epithelial cells derived from intestinal organoids and transcripto......
目的应用谱系重编程技术将表皮角质细胞转分化为汗腺样细胞,并在体外构建三维培养体系,诱导工程化的汗腺样细胞自组装为汗腺类器官......
Among somatic stem cells, those residing in the intestine represent a fascinating and poorly explored research field. Pa......
The introduction of biologics such as anti-tumor necrosis factor(TNF)monoclonal antibodies followed by anti-integrins ha......
Understanding the occurrence, development, and treatment of liver diseases is the main goal of hepatopathology research.......
The promises and challenges of patient‐derived tumor organoids in drug development and precision onc
In the era of precision medicine,cancer researchers and oncologists are eagerly searching for more realistic,cost effect......
目的建立小鼠肠腺瘤类器官的体外培养方法,观察其对电离辐射的反应。方法采用氧化偶氮甲烷(azoxymethane,AOM)和葡聚糖硫酸钠(detr......
类器官(Organoid)是应用体外三维(3-Dimensional,3D)培养技术建立的结构和功能上类似于器官的小型组织,具有组织自我更新及可长期......
BACKGROUND Retinal organoids serve as excellent human-specific disease models for conditions affecting otherwise inacces......
While the incidence and mortality of gastric cancer (GC) have declined due to public health programs, it remains the thi......
Induced pluripotent stem cells for therapy personalization in pediatric patients:Focus on drug-induc
Adverse drug reactions(ADRs)are major clinical problems,particularly in special populations such as pediatric patients.I......
Cerebral organoids exhibit mature neurons and astrocytes and recapitulate electrophysiological activ
Multiple protocols have been devised to generate cerebral organoids that recapitulate features of the developing human b......
New approaches to increase intestinal length:Methods used for intestinal regeneration and bioenginee
Inadequate absorptive surface area poses a great challenge to the patients suffering a variety of intestinal diseases ca......
