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Interleukin-18-induced inflammatory responses in synoviocytes and chondrocytes from osteoarthritic p
Objective The major pathological changes of osteoarthritis (OA) include cartilage degeneration and synovial inflammation......
Aim: This work was designed to investigate the potential molecular mechanism of Paeoniflorin (Pae) in inhibiting PGE2 in......
Shear stress triggered an increase in [Ca2+]i through Ca2+ influx by activating a TRPV4-like channel
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OBJECTIVE To investigate the potential molecular mechanism of Paeoniflorin (Pae) in inhibiting PGE2 induced human fibrob......
Paeoniflorin inhibits human fibroblast-like synoviocytes proliferation induced by PGE2 via arresting
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Celastrol inhibits interleukin-17A-stimulated rheumatoid fibroblast-like synoviocyte migration and i
Interleukin-17A (IL-17A)-induced migration and invasion of fibroblast-like synoviocytes (FLSs) is critical for the patho......
Purpose: Synovial membrane hyperplasia of rheumatoid arthritis (RA) is a critical pathological foundation for inducing a......
Effects of cytokines, growth factors and drugs on matrix metalloproteinases activities of osteoarthr
Objective: To evaluate the effects of some cytokines, TGF-β1 and drugs on matrix metalloproteinases (MMPs) activities i......
Expression of C5aR (CD88) of synoviocytes isolated from patients with rheumatoid arthritis and osteo
Objective To investigate the expression of anaphylatoxin receptor C5aR (CD88) in synoviocytes from patients with rheumat......
目的 探讨高迁移率族蛋白(high mobility group box,HMGB)1对大鼠滑膜细胞STAT信号通路的调控作用.方法 将常规培养大鼠滑膜细胞株......
目的 通过改良组织块细胞培养法,建立一种简单、可行的佐剂性关节炎兔成纤维样滑膜细胞(FLS)体外培养方法并观察细胞生物学特性.方法......
Triptolide Inhibits Expression of Inflammatory Cytokines and Proliferation of Fibroblast-like Synovi
Triptolide,a component of the Chinese herb Tripterygium wilfordii Hook F,has been proved to be effective in the treatmen......
Effects of cytokines, growth factors and drugs on matrix metalloproteinases activities of osteoarthr
Objective: To evaluate the effects of some cytokines, TGF-β1 and drugs on matrix metalloproteinases (MMPs) activities i......
目的:研究原花青素(PC)对佐剂关节炎大鼠滑膜细胞Bcl-2、Bax表达的影响。方法:采用大鼠佐剂性关节炎(AA)模型,逆转录聚合酶链反应(RT-PCR)测......
目的:研究脂多糖(LPS)诱导滑膜细胞产生一氧化氮(NO)及酪氨酸激酶(PTK)抑制剂木黄酮对其的抑制作用.方法:LPS或LPS+木黄酮体外刺激......
目的探讨在Synoviolin基因修饰滑膜细胞条件下预防肌腱粘连的效果。方法 36只Leghom鸡按随机数字表法分为实验组和对照组,每组18只......
目的:探讨三氧化二砷(AS2O3)对高迁移率族蛋白1(HMGB1)诱导的大鼠滑膜细胞(RSC-364细胞)增殖的抑制作用及其机制。方法:将常规培养的RSC-36......
以体外培养的大鼠关节炎模型的滑膜细胞为研究对象,用蛋白激酶C(PKC)激活剂佛波酯(phorbol 12-myristate 13-acetate,PMA)刺激细胞模拟......