VACCINE相关论文
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Thesevereacuterespiratorysyndromecoronavirus2(SARS-CoV-2)infectionhasresultedinnumerousconfirmedcasesanddeathsworldwide.......
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In October 2021,the World Health Organization(WHO)endorsed the first malaria vaccine,as a complementary tool for widespr......
Equity is not equality.The word\'equity\'focuses on the individual and takes a need-based approach,whereas\'equali......
The substantial advances attained by checkpoint blockade immunotherapies have driven an expansion in the approaches used......
Cytotoxic T cells targeting cancer neoantigens harboring driver mutations can lead to durable tumor regression in an HLA......
新型冠状病毒肺炎威胁着人民的生命健康和财产安全。新型冠状病毒肺炎疫苗是建立人群免疫屏障、实现疫情全球卫生治理的关键公共品......
The coronavirus disease 2019 (COVID-19) pandemic has been an unmitigated disaster for society and the economy worldwide.......
目的:建立可持续更新的全球疫苗安全性评价文献数据仓库,为疫苗安全性循证评价提供数据支持。方法:通过循证评价的标准操作步骤与人......
Objective:The coronavirus disease 2019 (COVID-19) pandemic has had a serious impact on health all over the world.Cancer ......
Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),the causative pathogen of the coronavirus disease 2019(COVID......
安全有效的疫苗是应对新型冠状病毒(新冠病毒)肺炎大流行的核心措施之一,从疫苗上市前安全性、保护效力的实验性研究到上市后安全性监......
Multiple myeloma (MM) is the second most common hematologic malignancy,and is characterized by the clonal expansion of m......
Exploration of a Sequential Gp140-Gp145 Immunization Regimen with Heterologous Envs to Induce a Prot
Raising a heterologous tier 2 neutralizing antibody (nAb) response remains a daunting task for HIV vaccine development.I......
A Recombinant Rabies Virus Expressing Fms-like Tyrosine Kinase 3 Ligand (Flt3L) Induces Enhanced Imm
Rabies is a zoonotic disease that still causes 59,000 human deaths each year,and rabies vaccine is the most effective wa......
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Preparation and immunogenicity of multivalent vaccines composed of recombinant SLS and fimbriae agai
Diarrhea in piglets is one of the most challenging problems in the swine industry and causes huge economic loss annually......
The excretory/secretory (ES) proteins ofschistosomes play important roles in modulating host immune systems and are rega......
Regulating the surface charges of polymeric microparticles to improve the efficacy of particles-adju
Biodegradable polymer-based micro/nanoparticles have been extensively investigated as vaccine adjuvants.Various characte......
Molecular Cloning, expression and purification of immunogenic proteins Pgi and Spb1 of Streptococcus
Streptococcus agalactiae, also known as Group B Streptococcus (GBS), is a major pathogen that causes serious infections ......
RNA interference and the vaccine effect of subolesin homolog from the tick Rhipicephalus haemaphysal
Subolesin is a well-characterized protective antigen in many ticks,and thus,is potentially useful in the development of ......
Recombinant canine adenovirus type-2 expressing TgROP16 provides partial protection against acute To
We have previously demonstrated the survival time of mice challenge with T.gondii RH strain was prolonged by immunizing ......
The preparation and preliminary application of virus-like particles (betanodavirus) in grouper, Epin
Nervous necrosis virus (NNV), which causes viral encephalopathy and retinopathy, is one of the most devastating viruses ......
Immunogenicity and Protective Efficacy of An Eimeria Vaccine Candidate Based on Eimeria tenella Immu
The CD40 ligand(CD40L)has shown potential as a powerful immunological adjuvant in various studies.Here,the efficacy of a......
Two potential recombinant rabies vaccines expressing canine parvovirus virion protein 2 induce immun
Both rabies virus (RABV) and canine parvovirus (CPV) cause lethal diseases in dogs.In this study, both high egg passage ......
Evaluation on the Efficacy and Immunogenicity of Recombinant swinepox virus expressing the A site of
To explore the development of a vaccine against transmissible gastroenteritis virus (TGEV) infections,the gene coding fo......
Improved antitumor efficacy of combined vaccine based on the induced HUVECs and DC-CT26 against colo
Objective Angiogenesis is essential for the development,growth,and metastasis of solid tumors....
目的 Aiming at the poor cellular response of aluminum adjuvant,we devoted ourselvesto exploring novel materials to impro......
目的 Spontaneous humoral and cell-mediated immune responses have been demonstrated against several cancer/testis antigen......
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Recombinant Trimeric H5N1-HA Vaccine Induces Protective Immunity that Primarily Targets the Receptor
Highly pathogenic avian influenza A virus H5N1 continues to spread among poultry and has frequently broken the species b......
The immune responses of HLA-A*0201 restricted SARSCoV S peptide-specific CD8 T cells are augmented i
The induction of antigen specific memory CD8+ T cells in vivo is very important to new vaccines against infectious disea......
Novel FbaA-and M protein-based multi-epitope vaccine elicits effective immune protection against gro
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Human respiratory syncytial virus(RSV),a negative-strand,non-segmented RNA virus,is the primary cause of viral lower res......
Background: Over 180 million individuals were chronically infected by hepatitis C virus(HCV),which poses great threats a......
Allogenic dendritic cell and tumor cell fused vaccine for targeted imaging and enhanced immunotherap
Background: Gastric cancer (GC) is the fourth most common cancer and ranks the third among all malignant tumors in China......
Cytokines Microparticels-In Situ Vaccination for Hepatocellular Carcinoma: In Vivo and In Vitro Resp
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The induction of antigen specific memory CD8+ T cells in vivo is very important to new vaccines against infectious disea......
Transcriptome analysis of gene expression profiling of infected macrophages between Brucella suis 13
Brucellosis is one of the most common zoonotic epidemics worldwide.Vaccination against brucellosis is an important contr......
The adjuvant effects of N-(2-hydroxypropyl)-3-trimethylammonium chitosan chloride to a hepatitis A v
Objective: Chitosan is a biodegradable,biocompatible and natural polymer with low immunogenicity that derived from chiti......
The present study cultured and separated breast cancer stem cells (CSCs) to produce a vaccine,and the safety and efficac......
Introduction In this trial, we isolated and cultured pancreatic cancer stem cells (CSCs) to produce a vaccine and prospe......
In this trial, nasopharyngeal cancer stem cells (CSCs)were separated and cultured to produce a vaccine;its safety and ef......
In this trial, lung cancer stem cells (CSCs) were separated and cultured to produce a vaccine;its safety and efficacy we......
Tumor-associated carbohydrate antigens(TACAs)are regarded as important targets for vaccine development.Vaccines based on......
Objective The aim of the study was to explore and contrast the immune efficacy of four Mycoplasma hyopneumoniae vaccines......