cannabinoid相关论文
Selective strengthening of synaptic inhibition between dentate cannabinoid-sensitive interneurons in
Altered inhibition is asalient featureof hippocampal network reorganization in epilepsy.Dentate granule cells show reduc......
Protein turnover and homeostasis is regulated by proteasomal system,which is essential in keeping cell viability and nor......
Aim: The purpose of the present study was to define the effects of N-arachid0nylethanolamine (anandamide), an endogenous......
Cannabis is an annual flowering herb.It is widely known for its ability in producing cognitive and emotional effects.The......
The orexin system is involved in the regulation of pain,in addition to arousal,feeding and reward.Here,we revealed a nov......
BACKGROUND Antagonists of cannabinoid type 1 receptor(CB1)have been shown to promote body weight loss and improve insuli......
Chronic use of antipsychotic medications entails a dilemma between the benefit of alleviating psychotic symptoms and the......
<span style=“font-family:”“><span style=”font-family:Verdana;\">Here in the United States Cannabidiol (CBD) is leg......
<strong>Introduction:</strong> Because of the rising prevalence of cannabis abuse, cannabinoid hyperemesis syndrome (CHS......
目的评价大麻素2型受体(CB2R)在七氟烷后处理减轻大鼠肠缺血再灌注损伤中的作用。方法清洁级健康雄性SD大鼠24只，8～10周龄，体重220～270......
Cannabinoid CB_(2) receptors and spinal microglia are implicated in tingenone-mediated antinocicepti
Objective:To investigate the antinociceptive effect of tingenone on inflammatory pain,as well as and the involvement of ......
Inhibitory effects of synthetic cannabinoid WIN55, 212-2 on nicotine-activated currents in rat trige
Cannabinoid and nicotinic acetylcholine receptors are strongly associated with algesia. Previous studies in our laborato......
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Cannabis is a common drug of abuse that is associated with various long-term and short-term adverse effects.The nature o......
The impact of cannabinoid type 2 receptors (CB2Rs) in neuroprotection against neurological disorders
Cannabinoids have long been used for their psychotropic and possible medical properties of symptom relief.In the past fe......
,Heterogeneity of cannabinoid ligand-induced modulations in intracellular Ca2+ signals of mouse panc
We recently reported that a CB2R agonist,GW405833 (GW),reduced both the ACh-induced Ca2+ oscillations and the L-arginine......
,CB2 receptor antibody signal specificity: correlations with the use of partial CB2-knockout mice an
Cannabinoid CB1 receptors are highly expressed in the brain and functionally modulate presynaptic neurotransmitter relea......
,Computational systems pharmacology analysis of cannabidiol:a combination of chemogenomics-knowledge
With treatment benefits in both the central nervous system and the peripheral system,the medical use of cannabidiol (CBD......
Pharmacological characterizationof synthetic cannabinoid MAM-2201:radioligand binding and abuse-rela
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
目的分析奎硫平对慢性酒精中毒大鼠海马谷氨酸含量及大麻素受体1（CB1）表达的影响。方法将48只大鼠按随机数字表法分为对照组、酒精中......
Inhibitory effects of synthetic cannabinoid WIN55, 212-2 on nicotine-activated currents in rat trige
Cannabinoid and nicotinic acetylcholine receptors are strongly associated with algesia. Previous studies in our laborato......
目的 探讨大麻素2型受体(CB2受体)在色素痣及皮肤恶性黑素瘤中的表达规律及其意义.方法 免疫组化、RT-PCR检测色素痣和恶性黑素瘤......
目的 探讨大麻素受体2( cannabinoid receptor 2,CB2R)激动剂JWH015对瑞芬太尼诱发的切口痛模型大鼠痛觉过敏的影响.方法 60只雄性......
目的:探讨大麻素WIN55,212-2(WIN)对裸小鼠肝癌移植瘤及过氧化物酶体增殖物激活受体(PPARγ)、c-myc表达的影响。方法:采用5 mg/kg......
目的 评价大麻素受体2(CB2受体)在谷氨酸诱发小胶质细胞损伤中的作用.方法 采用随机数字表法,将小胶质细胞随机分为4组:对照组(C组......
目的：探讨大麻素1型受体（ CB1R）在子宫内膜异位囊肿组织神经生长中的作用。方法利用免疫荧光和免疫印迹方法检测CB1R激动剂、阻断剂对......
据史料记载,早在公元200年前中国已将大麻(cannabis)用于镇痛及其他疾病的治疗,随后人们在娱乐和宗教活动中也开始使用大麻。随着......
目的：研究大麻素受体1（CB1）拮抗剂利莫那班对肝纤维化模型C57小鼠肝组织中CB1、α-平滑肌肌动蛋白（α-SMA）表达的影响，及其抗肝纤维化的......
目的：研究大麻素受体1（CB1）拮抗剂利莫那班对肝纤维化模型C57小鼠肝组织中CB1、α-平滑肌肌动蛋白（α-SMA）表达的影响，及其抗肝纤维化的......
AIM To investigate the anti-inflammatory effect and the possible mechanisms of an agonist of cannabinoid(CB) receptors, ......
目的研究大麻素受体1（CB1）mRNA在肝纤维化形成过程中表达的变化，从基因转录水平探讨其与细胞外信号调节激酶（ERK）的关系。方法采用10％四......
目的动态观察内源性大麻素受体l（CB1）在大鼠非酒精性脂肪性肝病（NAFLD）中的表达,初步探讨CB1在NAFLD发病中的作用。方法雄性SD大鼠48只......
内源性大麻素系统是近年来研究较为深入的一个脂质信号和神经调节系统,广泛参与了体内一些生理或病理过程的调节。大量的研究表明,......
目的探讨大麻素受体激动剂WIN55,212-2重复预处理对大鼠局灶性脑缺血再灌注损伤的保护作用。方法将50只雄性SD大鼠随机分为5组（n=10......
目的研究Anandamide（ANA）-大麻受体Ⅰ（CB1）在内脏高敏感形成中的作用及其机制。方法采用鸡卵清蛋白（OVA）腹腔注射基础致敏,联合非伤害性/......
目的：探讨大麻素（WIN55，212-2）点眼治疗是否可以抑制慢性青光眼兔模型玻璃体谷氨酸浓度的增高。方法：家兔15只随机分为正常对照组，高眼压......
Signal Peptide and Denaturing Temperature are Critical Factors for Efficient Mammalian Expression an
Many researchers employed mammalian expression system to artificially express can-nabinoid receptors, but immunoblot dat......
Inhibitory effects of synthetic cannabinoid WIN55, 212-2 on nicotine-activated currents in rat trige
Cannabinoid and nicotinic acetylcholine receptors are strongly associated with algesia.Previous studies in our laborator......
目的研究大麻素Ⅱ型(CB2)受体激活对1-甲基-4-苯基吡啶离子(MPP +)致SH-SY5Y细胞损伤的保护作用。方法 根据药物处理的不同将细胞......
在这篇文章，作者在在作者说的美国保存健康改革在疾病预防的角色上评论说健康提升和疾病预防编程序，这经常是常识，低技术、直接，但是成......
Neurodegenerative diseases are characterized by progressive degeneration and/or death of neuronal cells and results in a......
Activation of cannabinoid receptor CB2 regulates LPS-induced pro-inflammatory cytokine production an
Background and Objective: It has been found that human periodontal ligament (hPDL) cells express cannabinoid receptor CB......
CB1 receptor activation on VgluT2-expressing glutamatergic neurons underlies Δ9-tetrahydrocannabinol
OBJECTIVE Cannabis can be rewarding or aversive. Cannabis reward is believed to be mediated by activation of cannabinoid......
Long-Term Monoacylglycerol Lipase Inhibitor Treatment Decelerates Pathological Changes in APP/PS1-21
The arachidonic acid (AA) pathway produces several essential proinflammatory eicosanoids. However, in many neurodegenera......
Pharmacological inhibition of cannabinoid receptor 1 stimulates gastric release of nesfatin-1 via th
AIM To determine whether Nucb2/nesfatin1 production is regulated by the cannabinoid system through the intracellular m T......
[摘要] 目的 探讨大麻素Ⅱ型受体（CB2受体）激活对1-甲基-4-苯基-吡啶离子（MPP+）诱导原代星形胶质细胞炎症反应的影响。方法 培养原代星......
OBJECTIVE To detect the underlying mechanism of time window for estrogen (E2) replacement treating cognitive decline. ME......
缺血性卒中可导致严重的中枢神经系统损伤,病死率高,且预后差。大麻素2型受体不仅分布在外周免疫器官和细胞中,在脑中也具有一定的......
利莫纳班是选择性的大麻素CB1受体阻滞药，具有抑制进食、减轻体重、帮助戒烟、改善血脂代谢和糖代谢等作用。利莫纳班治疗肥胖研究......
Anandamide Depresses Glycinergic and GABAergic Inhibitory Transmissions in Adult Rat Substantia Gela
Cannabinoid CB1 receptors have been found in the superficial dorsal horn of the spinal cord, particularly the substantia......
