chiglitazar相关论文
Chiglitazar(Carfloglitazar)is a novel peroxisome proliferator-activated receptor(PPAR)pan-agonist that has shown promisi......
Efficacy and safety of chiglitazar,a novel peroxisome proliferator-activated receptor pan-agonist,in
Chiglitazar(Carfloglitazar)is a novel non-thiazolidinedione(TZD)structured peroxisome proliferator-activated receptor(PP......
目的:合成新的胰岛素增敏剂西格列羧[(2S)-2-[2-(4-氟苯甲酰)苯胺]-3-{[4-(2-咔唑-9-基)-乙氧基]苯基}丙酸].方法:以4-氟苯甲酰环......
目的研究拟治疗2型糖尿病的创新化合物西格列他钠(chiglitazar)的体外代谢速率、代谢酶和代谢转化,为临床应用提供参考。方法采用高效......
目的研究治疗糖尿病新药西格列羧长期毒性剂量下,原形药物在比格犬体内的毒代动力学,以评价西格列羧的全身暴露水平,确定暴露水平......